A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer
一种通过组织特异性敲除p53和Brca1基因构建的小鼠模型,其乳腺肿瘤在基因组和转录组上与人类基底样乳腺癌具有相似性。
期刊:Breast Cancer Research and Treatment
影响因子:3
doi:10.1007/s10549-018-5061-y
Hollern, Daniel P; Contreras, Cristina M; Dance-Barnes, Stephanie; Silva, Grace O; Pfefferle, Adam D; Xiong, Jessie; Darr, David B; Usary, Jerry; Mott, Kevin R; Perou, Charles M