日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Endocannabinoid Enhancement via MAGL Inhibition in CDKL5 Deficiency: Selective Cellular Benefits and Domain-Specific Functional Effects in Adult Cdkl5 KO Mice

CDKL5 缺陷中通过 MAGL 抑制增强内源性大麻素：成年 Cdkl5 KO 小鼠的选择性细胞获益和结构域特异性功能效应

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27062773
Loi, Manuela; Mottolese, Nicola; Medici, Giorgio; Iannibelli, Feliciana; Interino, Nicolò; Candini, Giulia; Trebbi, Federica; Bove, Angelica Marina; Fiori, Jessica; Trazzi, Stefania; Ciani, Elisabetta
MAG
细胞生物学
发表日期：2026
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Safety and efficacy of Igk-TATk-CDKL5 gene therapy in mosaic CDKL5 deficiency

Igk-TATk-CDKL5基因疗法治疗嵌合型CDKL5缺陷的安全性和有效性

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2025.e00727
Medici, Giorgio; Tassinari, Marianna; Loi, Manuela; Bove, Angelica Marina; Garofani, Beatrice Casadei; Volpedo, Greta; Mottolese, Nicola; Matteoli, Gabriele; Lo Martire, Viviana; Berteotti, Chiara; Candini, Giulia; Trebbi, Federica; Riva, Antonella; Striano, Pasquale; Zoccoli, Giovanna; Curia, Giulia; Trazzi, Stefania; Ciani, Elisabetta
发表日期：2025
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Lactic acid bacteria as microbial cell factories for the in vivo delivery of therapeutic proteins as secretable TAT fusion products

乳酸菌作为微生物细胞工厂，用于体内递送治疗性蛋白，以分泌型TAT融合产品的形式存在。

期刊:Journal of Biological Engineering
影响因子:6.5
doi:10.1186/s13036-025-00538-4
Medici, Giorgio; Candini, Giulia; Mottolese, Nicola; Uguagliati, Beatrice; Trebbi, Federica; Loi, Manuela; Bove, Angelica Marina; Stojanov, Spase; Esposito, Erika; Vitagliano, Rosalba; D'Amico, Federica; Turroni, Silvia; Fiori, Jessica; Berlec, Aleš; Trazzi, Stefania; Ciani, Elisabetta
微生物学
细胞生物学
发表日期：2025
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Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice

成年小鼠前脑谷氨酸能神经元中 CDKL5 基因缺失会损害突触完整性和行为

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26146626
Mottolese, Nicola; Iannibelli, Feliciana; Candini, Giulia; Trebbi, Federica; Loi, Manuela; Bove, Angelica Marina; Medici, Giorgio; Xiong, Zhi-Qi; Ciani, Elisabetta; Trazzi, Stefania
神经科学
发表日期：2025
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Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder

辅酶Q10在CDKL5缺乏症体外和体内模型中的有益抗氧化作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26052204
Loi, Manuela; Valenti, Francesca; Medici, Giorgio; Mottolese, Nicola; Candini, Giulia; Bove, Angelica Marina; Trebbi, Federica; Pincigher, Luca; Fato, Romana; Bergamini, Christian; Trazzi, Stefania; Ciani, Elisabetta
发表日期：2025
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A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids

针对 CDKL5 缺乏症的交叉矫正基因治疗方法改善了 CDD 患者来源的皮质类器官的病理表型

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.8
doi:10.3389/fbioe.2025.1744903
Medici, Giorgio; Bove, Angelica M; Trazzi, Stefania; Puppo, Francesca; Loi, Manuela; Mottolese, Nicola; Candini, Giulia; Trebbi, Federica; Sanchez, Sandra; Muotri, Alysson R; Ciani, Elisabetta
3D/类器官
基因治疗
CDD
发表日期：2025
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Causally Mapping the Cerebellum in Children and Young Adults: from Motor to Cognition

儿童和青少年小脑因果关系图谱：从运动到认知

期刊:Cerebellum
影响因子:2.4
doi:10.1007/s12311-024-01778-8
Veyrie, Marina; Beffara, Bertrand; Richard, Nathalie; Mottolese, Carmine; Szathmari, Alexandru; Di Rocco, Federico; Faure Conter, Cécile; Leblond, Pierre; Desmurget, Michel; Cristofori, Irene; Beuriat, Pierre-Aurélien
神经科学
发表日期：2025
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Craniopharyngiomas in children: the pendulum moves again for an aggressive surgery-late complications and considerations with a recent series of 26 patients treated in Lyon

儿童颅咽管瘤：手术治疗的风向再次转变——晚期并发症及相关考量：以里昂近期治疗的26例患者为例

期刊:Childs Nervous System
影响因子:1.2
doi:10.1007/s00381-025-06815-3
Beuriat, Pierre-Aurélien; Szathmari, Alexandru; Di Rocco, Federico; Villanueva, Carine; Bazus, Lucie; Cabet, Sara; Veyrie, Marina; Mottolese, Carmine
发表日期：2025
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Benign brainstem tumors in children: a retrospective series of 42 patients treated in Lyon

儿童良性脑干肿瘤：里昂42例患者的回顾性研究

期刊:Childs Nervous System
影响因子:1.2
doi:10.1007/s00381-025-06908-z
Beuriat, P A; Boukaka, R G; Szathmari, A; Vasiljevic, A; Di Rocco, F; Mottolese, C
肿瘤
肿瘤免疫
神经科学
发表日期：2025
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Impact of SMAD6 Variants on Neurodevelopment in Craniosynostosis

SMAD6 变异对颅缝早闭症神经发育的影响

期刊:Journal of Craniofacial Surgery
影响因子:1
doi:10.1097/SCS.0000000000011461
Verlut, Isabelle; Guernouche, Sofia; Rossi, Massimiliano; Szathmari, Alexandru; Beuriat, Pierre A; Chatron, Nicolas; Chauvel-Picard, Julie; Mottolese, Carmine; Monin, Pauline; Vinchon, Matthieu; Collet, Corinne; Di Rocco, Federico
发育与干细胞
神经科学
发表日期：2025
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