Aconitine outperforms mesaconitine and hypaconitine in triggering excessive mitophagy via lysosomal two-pore channels disruption in SH-SY5Y cells and zebrafish.
在 SH-SY5Y 细胞和斑马鱼中，乌头碱通过破坏溶酶体双孔通道来触发过度线粒体自噬，其效果优于中乌头碱和次乌头碱。
期刊:Toxicology Research
影响因子:2.1
doi:10.1093/toxres/tfag008
Feng Han, Mou Qiaoxing, Yan Xiaoyu, Zhang Zijian, Liang Tianyu, Peng Fu, Zhang Tingting, Yan Mengfan, Liang Jie, Liu Weiying, Tang Huayang, Peng Cheng, Pan Xiaoqi
