日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites

通过抑制剂可及结合位点增强脱辅基蛋白酪氨酸磷酸酶非受体型2晶体浸泡策略

Bester, Stephanie M; Linwood, Rebecca; Kataoka, Ryoko; Wu, Wen I; Mou, Tung Chung

Crystal structure of the GDP-bound human M-RAS protein in two crystal forms

人M-RAS蛋白GDP结合态的两种晶体结构的晶体结构

Bester, Stephanie M; Abrahamsen, Rebecca; Rodrigues Samora, Luiza; Wu, Wen I; Mou, Tung Chung

Application of sulfur SAD to small crystals with a large asymmetric unit and anomalous substructure

将硫SAD应用于具有大不对称单元和异常亚结构的微小晶体

Mou, Tung Chung; Zeng, Baisen; Doukov, Tzanko I; Sprang, Stephen R

The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a).

人类组蛋白赖氨酸 N-甲基转移酶 EHMT2 (G9a) 的富含半胱氨酸区域的结构

Kerchner Keshia M, Mou Tung-Chung, Sun Yizhi, Rusnac Domniţa-Valeria, Sprang Stephen R, Briknarová Klára

Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution

幽门螺杆菌空泡毒素A寡聚体组装体的近原子分辨率冷冻电镜结构

Zhang, Kaiming; Zhang, Huawei; Li, Shanshan; Pintilie, Grigore D; Mou, Tung-Chung; Gao, Yuanzhu; Zhang, Qinfen; van den Bedem, Henry; Schmid, Michael F; Au, Shannon Wing Ngor; Chiu, Wah

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

人c-MYC癌基因启动子区域形成的主要四链体的晶体结构

Stump, Sascha; Mou, Tung-Chung; Sprang, Stephen R; Natale, Nicholas R; Beall, Howard D

Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.

细胞色素c可以形成明确的碳氢化合物结合口袋

McClelland Levi J, Steele Harmen B B, Whitby Frank G, Mou Tung-Chung, Holley David, Ross J B Alexander, Sprang Stephen R, Bowler Bruce E

Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate

2',3'-O-(N-甲基邻氨基苯甲酰基)-肌苷5'-三磷酸对哺乳动物膜腺苷酸环化酶高亲和力抑制的结构基础

Hübner, Melanie; Dixit, Anshuman; Mou, Tung-Chung; Lushington, Gerald H; Pinto, Cibele; Gille, Andreas; Geduhn, Jens; König, Burkhard; Sprang, Stephen R; Seifert, Roland

Differential inhibition of various adenylyl cyclase isoforms and soluble guanylyl cyclase by 2',3'-O-(2,4,6-trinitrophenyl)-substituted nucleoside 5'-triphosphates

2',3'-O-(2,4,6-三硝基苯基)取代的核苷5'-三磷酸对各种腺苷酸环化酶同工酶和可溶性鸟苷酸环化酶的差异性抑制

Suryanarayana, Srividya; Göttle, Martin; Hübner, Melanie; Gille, Andreas; Mou, Tung-Chung; Sprang, Stephen R; Richter, Mark; Seifert, Roland

The high binding affinity of phosphorothioate-modified oligomers for Ff gene 5 protein is moderated by the addition of C-5 propyne or 2'-O-methyl modifications

硫代磷酸酯修饰的寡聚体与 Ff 基因 5 蛋白的高结合亲和力可通过添加 C-5 丙炔或 2'-O-甲基修饰来调节。

Mou, Tung-Chung; Gray, Donald M