Boswellic Acid and Low-Dose Radiation Attenuate Hepatic Carcinogenesis induced in Rats by Suppressing NF-κB/TNF-α/MAPK Signaling, Blocking Angiogenesis, and Inducing Apoptosis via JAK/STAT3 Downstream Granzyme-B and Caspase-3 Pathways
乳香酸和低剂量辐射通过抑制NF-κB/TNF-α/MAPK信号通路、阻断血管生成以及通过JAK/STAT3下游颗粒酶B和Caspase-3通路诱导细胞凋亡，从而减轻大鼠肝癌的发生。
期刊:Integrative Cancer Therapies
影响因子:2.8
doi:10.1177/15347354251413219
Alzoubi, Shefaa M; Alasmari, Moudi M; Ahmad, Saman A; Alshaeri, Heba K; Abuh-Odeh, Ala' M; Talib, Wamidh H; Elbakary, Nermeen M; Abdel-Rafei, Mohamed Khairy; Kayed, Azza E; Elbahnasawy, Mostafa A; Mansour, Mansour I
Rat
细胞生物学
肝癌
STAT3
肿瘤免疫
肿瘤
JAK/STAT
Apoptosis
MAPK/ERK
凋亡
Angiogenesis
信号转导
TNF-α
血管生成
NF-κB
表观遗传
