日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination.

USP37 通过 MCM 复合物去泛素化防止非计划的复制体卸载

Bolhuis Derek L, Fleifel Dalia, Bonacci Thomas, Wang Xianxi, Mouery Brandon L, Cook Jeanette Gowen, Brown Nicholas G, Emanuele Michael J

Dordaviprone/ONC201 Activation of the ClpP Mitochondrial Protease Inhibits the Growth of KRAS-Mutant Pancreatic Cancer and Overcomes RAS Inhibitor Resistance

多达维普隆/ONC201激活ClpP线粒体蛋白酶,抑制KRAS突变型胰腺癌的生长并克服RAS抑制剂耐药性。

Drizyte-Miller, Kristina; Degan, Seamus E; Mouery, Ryan D; Amparo, Amber M; Mouery, Brandon L; Chang, Wen-Hsuan; Yang, Runying; Nicewarner Peña, Sheila R; Baldelli, Elisa; Klomp, Jeffrey A; Iwanowicz, Edwin J; Graves, Lee M; Petricoin, Emanuel F; Cox, Adrienne D; Stalnecker, Clint A; Bryant, Kirsten L; Der, Channing J

Small Molecule Activators of the Mitochondrial Protease ClpP Induce Senescence in Triple-Negative Breast Cancer Cells and Sensitize Cells to the Bcl-2 Inhibitor Venetoclax

线粒体蛋白酶ClpP的小分子激活剂可诱导三阴性乳腺癌细胞衰老,并使细胞对Bcl-2抑制剂维奈托克敏感。

Daglish, Sabrina C D; Canterbury, Owen G; Graves, Paul R; Carter, Sarah A; Beese, Sydney M; Hynek, Maggie A; Mouery, Brandon L; Mistreanu, Andrei J; Bhatt, Aadra P; Tellez, Nestor; Butler, Mitchell T; Aponte-Collazo, Lucas J; Fennell, Emily M J; Herring, Laura E; Lyons, Scott; Mills, C Allie; Ashamalla, Hani; Iwanowicz, Edwin J; Morris, John P 4th; Bear, James E; Greer, Yoshimi Endo; Lipkowitz, Stanley; Graves, Lee M

APC/C prevents a noncanonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

APC/C 可阻止细胞周期蛋白/CDK 活性的非经典顺序,从而维持 CDK4/6 抑制剂诱导的细胞周期阻滞。

Mouery, Brandon L; Baker, Eliyambuya M; Mei, Liu; Wolff, Samuel C; Mills, Christine A; Fleifel, Dalia; Mulugeta, Nebyou; Herring, Laura E; Cook, Jeanette Gowen

Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

蛋白质组学分析揭示了PLK1依赖的G2/M期降解程序以及AKAP2在协调有丝分裂细胞骨架中的作用

Ryan D Mouery ,Kimberly Lukasik ,Carolyn Hsu ,Thomas Bonacci ,Derek L Bolhuis ,Xianxi Wang ,C Allie Mills ,E Drew Toomer ,Owen G Canterbury ,Kevin C Robertson ,Timothy B Branigan ,Nicholas G Brown ,Laura E Herring ,Stephanie L Gupton ,Michael J Emanuele

USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination

USP37 通过 MCM 复合物去泛素化阻止非计划复制体卸载

Derek L Bolhuis, Dalia Fleifel, Thomas Bonacci, Xianxi Wang, Brandon L Mouery, Jeanette Gowen Cook, Nicholas G Brown, Michael J Emanuele

APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

APC/C 阻止细胞周期蛋白/CDK 活性的非规范顺序,以维持 CDK4/6 抑制剂诱导的停滞

Brandon L Mouery, Eliyambuya M Baker, Christine A Mills, Laura E Herring, Dalia Fleifel, Jeanette Gowen Cook

Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control

蛋白质组学分析揭示了 PLK1 依赖的 G2/M 降解程序,并将 PKA-AKAP2 与细胞周期控制联系起来

Ryan D Mouery, Carolyn Hsu, Thomas Bonacci, Derek L Bolhuis, Xianxi Wang, Christine A Mills, E Drew Toomer, Owen G Canterbury, Kevin C Robertson, Timothy B Branigan, Nicholas G Brown, Laura E Herring, Michael J Emanuele

CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

CDK4/6 抑制剂诱导复制压力导致长期细胞周期停滞

Lisa Crozier #, Reece Foy #, Brandon L Mouery, Robert H Whitaker, Andrea Corno, Christos Spanos, Tony Ly, Jeanette Gowen Cook, Adrian T Saurin

Quantitative profiling of adaptation to cyclin E overproduction

对细胞周期蛋白E过量生产的适应定量分析

Juanita C Limas, Amiee N Littlejohn, Amy M House, Katarzyna M Kedziora, Brandon L Mouery, Boyang Ma, Dalia Fleifel, Andrea Walens, Maria M Aleman, Daniel Dominguez, Jeanette Gowen Cook