日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins.

重新评估在透化血癌细胞上测试维奈托克或其他 BH3 模拟剂的试验,这些药物选择性地靶向促生存 BCL2 蛋白

Gong Jia-Nan, Djajawi Tirta M, Moujalled Donia M, Pomilio Giovanna, Khong Tiffany, Zhang Li-Ping, Fedele Pasquale L, Low Michael S, Anderson Mary Ann, Riffkin Christopher D, White Christine A, Lan Ping, Lessene Guillaume, Herold Marco J, Strasser Andreas, Spencer Andrew, Grigoriadis George, Wei Andrew H, van Delft Mark F, Roberts Andrew W, Huang David C S

Differential regulation of BAX and BAK apoptotic activity revealed by small molecules

小分子揭示BAX和BAK凋亡活性的差异调节

Kaiming Li, Yu Q Yap, Donia M Moujalled, Fransisca Sumardy, Yelena Khakham, Angela Georgiou, Michelle Jahja, Thomas E Lew, Melanie De Silva, Meng-Xiao Luo, Jia-Nan Gong, Zheng Yuan, Richard W Birkinshaw, Peter E Czabotar, Kym Lowes, David C S Huang, Benjamin T Kile, Andrew H Wei, Grant Dewson, Mark

Metabolic Plasticity of Glioblastoma Cells in Response to DHODH Inhibitor BAY2402234 Treatment

胶质母细胞瘤细胞对 DHODH 抑制剂 BAY2402234 治疗的代谢可塑性

Ayenachew Bezawork-Geleta, Diane Moujalled, David P De Souza, Vinod K Narayana, James Dimou, Rodney Luwor, Matthew J Watt

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia.

BAX 基因的获得性突变可使急性髓系白血病对 BH3 模拟疗法产生耐药性

Moujalled Donia M, Brown Fiona C, Chua Chong Chyn, Dengler Michael A, Pomilio Giovanna, Anstee Natasha S, Litalien Veronique, Thompson Ella, Morley Thomas, MacRaild Sarah, Tiong Ing S, Morris Rhiannon, Dun Karen, Zordan Adrian, Shah Jaynish, Banquet Sebastien, Halilovic Ensar, Morris Erick, Herold Marco J, Lessene Guillaume, Adams Jerry M, Huang David C S, Roberts Andrew W, Blombery Piers, Wei Andrew H

Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

更正:抗癌药物APR-246可激活多种程序性细胞死亡过程以杀死恶性细胞。

Wang, Zilu; Hu, Huimin; Heitink, Luuk; Rogers, Kelly; You, Yue; Tan, Tao; Suen, Connie Li Wai; Garnham, Alex; Chen, Hao; Lieschke, Elizabeth; Diepstraten, Sarah T; Chang, Catherine; Chen, Tianwei; Moujalled, Diane; Sutherland, Kate; Lessene, Guillaume; Sieber, Oliver M; Visvader, Jane; Kelly, Gemma L; Strasser, Andreas

The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

抗癌药物APR-246可以激活多种程序性细胞死亡过程来杀死恶性细胞

Zilu Wang, Huimin Hu, Luuk Heitink, Kelly Rogers, Yue You, Tao Tan, Connie Li Wai Suen, Alex Garnham, Hao Chen, Elizabeth Lieschke, Sarah T Diepstraten, Catherine Chang, Tianwei Chen, Diane Moujalled, Kate Sutherland, Guillaume Lessene, Oliver M Sieber, Jane Visvader, Gemma L Kelly, Andreas Strasser

Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

促炎微环境促进巨核细胞和TPO水平高的小鼠淋巴瘤进展

Au, Amanda E; Corbin, Jason; Lebois, Marion; Gangatirkar, Pradnya; Yassinson, Fatme; Hyslop, Stephanie R; Cannon, Ping; Mason, Kylie D; Li-Wai-Suen, Connie S N; Garnham, Alexandra L; Moujalled, Diane; Cimmino, Luisa; Alexander, Warren S; Josefsson, Emma C

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

BH3 模拟药物与替莫唑胺、JQ1 和铁死亡诱导剂协同杀死多形性胶质母细胞瘤细胞

Diane Moujalled, Adam G Southon #, Eiman Saleh #, Kerstin Brinkmann, Francine Ke, Melinda Iliopoulos, Ryan S Cross, Misty R Jenkins, Duong Nhu, Zilu Wang, Melissa X Shi, Ruth M Kluck, Guillaume Lessene, Stephanie Grabow, Ashley I Bush, Andreas Strasser

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

完整的 TP-53 功能对于维持白血病对 BH3 模拟药物的持久反应至关重要

Rachel Thijssen, Sarah T Diepstraten, Donia Moujalled, Edward Chew, Christoffer Flensburg, Melissa X Shi, Michael A Dengler, Veronique Litalien, Sarah MacRaild, Maoshan Chen, Natasha S Anstee, Boris Reljić, Sarah S Gabriel, Tirta M Djajawi, Chris D Riffkin, Brandon J Aubrey, Catherine Chang, Lin Tai

Molecular mechanisms of cell death in neurological diseases

神经系统疾病中细胞死亡的分子机制

Moujalled, Diane; Strasser, Andreas; Liddell, Jeffrey R