日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Tyrosine kinase inhibitor, masitinib, limits neuronal damage, as measured by serum neurofilament light chain concentration in a model of neuroimmune-driven neurodegenerative disease.

酪氨酸激酶抑制剂马西替尼可限制神经损伤，这可以通过在神经免疫驱动的神经退行性疾病模型中血清神经丝轻链浓度来衡量

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0322199
Hermine Olivier, Gros Laurent, Tran Truong-An, Loussaief Lamya, Flosseau Kathleen, Moussy Alain, Mansfield Colin D, Vermersch Patrick
神经科学
发表日期：2025
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Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial

马西替尼治疗轻度至中度阿尔茨海默病：一项随机、安慰剂对照的3期临床试验结果

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-023-01169-x
Dubois, Bruno; López-Arrieta, Jesús; Lipschitz, Stanley; Doskas, Triantafyllos; Spiru, Luiza; Moroz, Svitlana; Venger, Olena; Vermersch, Patrick; Moussy, Alain; Mansfield, Colin D; Hermine, Olivier; Tsolaki, Magda
阿尔茨海默症
发表日期：2023
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Correction: Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial

更正：马西替尼治疗轻度至中度阿尔茨海默病：一项随机、安慰剂对照的3期临床试验结果

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-023-01230-9
Dubois, Bruno; López-Arrieta, Jesús; Lipschitz, Stanley; Doskas, Triantafyllos; Spiru, Luiza; Moroz, Svitlana; Venger, Olena; Vermersch, Patrick; Moussy, Alain; Mansfield, Colin D; Hermine, Olivier; Tsolaki, Magda
阿尔茨海默症
发表日期：2023
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Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis: A Randomized, Phase 3, Clinical Trial

马西替尼治疗进展型多发性硬化症的疗效和安全性：一项随机、3期临床试验

期刊:Neurology-Neuroimmunology & Neuroinflammation
影响因子:7.5
doi:10.1212/NXI.0000000000001148
Vermersch, Patrick; Brieva-Ruiz, Luis; Fox, Robert J; Paul, Friedemann; Ramio-Torrenta, Lluis; Schwab, Matthias; Moussy, Alain; Mansfield, Colin; Hermine, Olivier; Maciejowski, Maciej
神经科学
多发性硬化症
发表日期：2022
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Efficacy and Safety of Masitinib in Corticosteroid-Dependent Severe Asthma: A Randomized Placebo-Controlled Trial

马西替尼治疗皮质类固醇依赖性重度哮喘的疗效和安全性：一项随机安慰剂对照试验

期刊:Journal of Asthma and Allergy
影响因子:3
doi:10.2147/JAA.S337284
Davidescu, Lavinia; Ursol, Grigoriy; Korzh, Oleksii; Deshmukh, Vikranth; Kuryk, Lesia; Nortje, Monja-Marie; Godlevska, Olga; Devouassoux, Gilles; Khodosh, Eduard; Israel, Elliot; Moussy, Alain; Mansfield, Colin D; Hermine, Olivier; Chanez, Pascal
哮喘
发表日期：2022
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Long-term survival analysis of masitinib in amyotrophic lateral sclerosis

马西替尼治疗肌萎缩侧索硬化症的长期生存分析

期刊:Therapeutic Advances in Neurological Disorders
影响因子:4.1
doi:10.1177/17562864211030365
Mora, Jesus S; Bradley, Walter G; Chaverri, Delia; Hernández-Barral, María; Mascias, Javier; Gamez, Josep; Gargiulo-Monachelli, Gisella M; Moussy, Alain; Mansfield, Colin D; Hermine, Olivier; Ludolph, Albert C
发表日期：2021
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Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study

马西替尼治疗进展型多发性硬化症患者：一项随机试点研究

期刊:BMC Neurology
影响因子:2.2
doi:10.1186/1471-2377-12-36
Vermersch, Patrick; Benrabah, Rabah; Schmidt, Nicolas; Zéphir, Hélène; Clavelou, Pierre; Vongsouthi, Cyrille; Dubreuil, Patrice; Moussy, Alain; Hermine, Olivier
神经科学
多发性硬化症
发表日期：2012
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Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial

马西替尼作为轻度至中度阿尔茨海默病辅助治疗：一项随机、安慰剂对照的 II 期试验

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/alzrt75
Piette, François; Belmin, Joël; Vincent, Hélène; Schmidt, Nicolas; Pariel, Sylvie; Verny, Marc; Marquis, Caroline; Mely, Jean; Hugonot-Diener, Laurence; Kinet, Jean-Pierre; Dubreuil, Patrice; Moussy, Alain; Hermine, Olivier
阿尔茨海默症
发表日期：2011
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Masitinib in the treatment of active rheumatoid arthritis: results of a multicentre, open-label, dose-ranging, phase 2a study

马西替尼治疗活动性类风湿性关节炎：一项多中心、开放标签、剂量探索性 2a 期研究的结果

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/ar2740
Tebib, Jacques; Mariette, Xavier; Bourgeois, Pierre; Flipo, René-Marc; Gaudin, Philippe; Le Loët, Xavier; Gineste, Paul; Guy, Laurent; Mansfield, Colin D; Moussy, Alain; Dubreuil, Patrice; Hermine, Olivier; Sibilia, Jean
关节炎
发表日期：2009
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Phenotypic and genotypic characteristics of mastocytosis according to the age of onset

根据发病年龄划分的肥大细胞增多症的表型和基因型特征

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0001906
Lanternier, Fanny; Cohen-Akenine, Annick; Palmerini, Fabienne; Feger, Frédéric; Yang, Ying; Zermati, Yael; Barète, Stéphane; Sans, Beatrix; Baude, Cédric; Ghez, David; Suarez, Felipe; Delarue, Richard; Casassus, Philippe; Bodemer, Christine; Catteau, Adeline; Soppelsa, Frédérique; Hanssens, Katia; Arock, Michel; Sobol, Hagay; Fraitag, Sylvie; Canioni, Danièle; Moussy, Alain; Launay, Jean Marie; Dubreuil, Patrice; Hermine, Olivier; Lortholary, Olivier
细胞生物学
肥大细胞
发表日期：2008
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