日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ctDNA Dynamics and Recurrence Patterns after Organ-Sparing Trimodality Therapy for Bladder Cancer

膀胱癌器官保留三联疗法后ctDNA动态变化及复发模式

Epstein, Ilana B; Odogiyon, Adetolani; Berg, Stephanie; Otani, Yukako; Mantia, Charlene; Pompa, Isabella R; Mossanen, Matthew; Wan, Joshua; Saraf, Anurag; Preston, Mark; Ravi, Arvind; Carvalho, Filipe; Herberts, Cameron; ElNaggar, Adam; Clinton, Timothy; Roberts, Daniel; Peng, Luke; McGregor, Bradley; Bellmunt, Joaquim; Kamran, Sophia C; Berchuck, Jacob E; Efstathiou, Jason A; Miyamoto, David T; Mouw, Kent W

KDM6 Enzymes are the Mechanistic Targets of Mutant IDH that Dictate Replication Stress Sensitivity

KDM6酶是突变型IDH的机制靶点,决定复制应激敏感性。

Tsai, Alexander C-Y; Lin, Mathew D; Puliyappadamba, Vinesh T; Junginger, Dorothy M; Donovan, Victoria G; Kaplan, Eleanor G; Drepanos, Laura M; Wakimoto, Hiroaki; Cahill, Daniel P; Losman, Julie A; Mouw, Kent W; Abdullah, Kalil G; Doench, John G; Nash, Duane; Vitt, Daniel; Gege, Christian; Kohlhof, Hella; McBrayer, Samuel K; Kaelin, William G; Shi, Diana D

Clinical and genomic profiling of early-onset bladder cancer identifies key alterations and therapeutic targets

对早期膀胱癌进行临床和基因组分析,可识别关键改变和治疗靶点。

Magnani, Christopher J; D'Andrea, Vincent D; Barros, Guilherme Garcia; Qian, Zhiyu; Ernandez, John; Yim, Kendrick; Kibel, Adam S; Chang, Steven L; Mossanen, Matthew; Preston, Mark A; Feldman, Adam S; Bochner, Bernard H; Solit, David B; Pietzak, Eugene J; Mouw, Kent W; Carvalho, Filipe L F; Clinton, Timothy N

Identification of an ERCC2 mutation associated mutational signature of nucleotide excision repair deficiency in targeted panel sequencing data

在靶向测序数据中鉴定出与核苷酸切除修复缺陷相关的ERCC2突变突变特征

Stojkova, Olivera; Börcsök, Judit; Sztupinszki, Zsofia; Diossy, Miklos; Prosz, Aurel; Neil, Alexander; Mouw, Kent W; Sørensen, Claus S; Szallasi, Zoltan

Quantitative functional profiling of ERCC2 mutations deciphers cisplatin sensitivity in bladder cancer.

ERCC2 突变的定量功能分析揭示了膀胱癌对顺铂的敏感性

Börcsök Judit, Gopaul Diyavarshini, Devesa-Serrano Daphne, Mooser Clémence, Jonsson Nicolas, Cagiada Matteo, Stormoen Dag R, Ataya Maya N, Guercio Brendan J, Kaimakliotis Hristos Z, Iyer Gopa, Lindorff-Larsen Kresten, Dyrskjøt Lars, Mouw Kent W, Szallasi Zoltan, Sørensen Claus S

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601

DNA损伤反应基因改变、分子亚型与CALGB 90601研究中转移性膀胱癌患者生存结局之间的关系

Iyer, Gopa; Choi, Woonyoung; Luo, Bin; Carvalho, Filipe; Hanlon, Timothy; Reis, Henning; Guercio, Brendan J; Fong, Megan; Mountain, Jack; Feng, Mingxiao; Regazzi, Ashley M; McCart, Linda; Wen, Yujia; Al-Ahmadie, Hikmat; Mouw, Kent W; Van Allen, Eliezer M; Bellmunt, Joaquim; Dreicer, Robert; Flaig, Thomas W; Halabi, Susan; McConkey, David J; Rosenberg, Jonathan E

Impact of DNA repair deficiency on sensitivity to antibody-drug conjugate (ADC) payloads in bladder cancer

DNA修复缺陷对膀胱癌抗体药物偶联物(ADC)有效载荷敏感性的影响

P Shanmugam, Surish; Zhou, Yuzhen; Stelter, Isabella; Hanlon, Timothy; Bekele, Raie T; Bellmunt, Joaquim; Szallasi, Zoltan; Mouw, Kent W

Orthotopic bladder cancer preclinical models: Comprehensive review and technique optimization

原位膀胱癌临床前模型:综合综述与技术优化

Hanlon, Timothy; D'Andrea, Vincent D; Stelter, Isabella; Bekele, Raie; Zhou, Yuzhen; Mouw, Kent W

Tumor B cell infiltration in platinum-treated advanced urothelial carcinoma

铂类药物治疗的晚期尿路上皮癌中肿瘤B细胞浸润

Stawiski, Konrad; Perera-Bel, Júlia; Rodriguez-Vida, Alejo; Juanpere Rodero, Núria; Lee, Jihyun; Michaud, Daniel E; Guerriero, Jennifer L; Mouw, Kent W; Bamias, Aristotelis; Carvalho, Filipe Lf; Bellmunt, Joaquim

APOBEC3A-Induced DNA Damage Drives Polymerase θ Dependency and Synthetic Lethality in Cancer.

APOBEC3A 诱导的 DNA 损伤驱动聚合酶 α 依赖性和癌症中的合成致死性。

Bose Abhishek, Liu Weisi, Yoo Paul, Sami Alina, Boniecki Michal T, Deshpande Madhura, Osman Mohamed, Nguyen Duy, Castillo Urko D, Giannakakou Paraskevi, Bhinder Bhavneet, Hooper William, Elemento Olivier, Robine Nicolas, Rodriguez Milaid Granadillo, Gerhardt Jeannine, Mouw Kent W, Chelico Linda, Faltas Bishoy M