Mpakali相关文献与解析，生知库 | 链接生命科学的每一步

Foscolos, Angeliki S; Pappas, Alexandros; Petroulias, Christos N; Kapella, Anna; Prifti, Georgia M; Zoidis, Grigoris; Papadopoulos, Minas; Mpakali, Anastasia; Chiotellis, Aristeidis

IDO

发表日期：2026

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Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

ER 氨基肽酶 1 的自身免疫保护同种型 10 的多态性位置 349 和 725 是决定其独特酶特性的关键

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2024.1415964

Galateia Georgaki, Anastasia Mpakali, Myrto Trakada, Athanasios Papakyriakou, Efstratios Stratikos

免疫

发表日期：2024

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Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor

新型底物选择性小分子抑制剂对胰岛素调节氨基肽酶开放构象的稳定

期刊:Protein Science

影响因子:4.5

doi:10.1002/pro.5151

Anastasia Mpakali, Galateia Georgaki, Alberto Buson, Alison D Findlay, Jonathan S Foot, Francois-Xavier Mauvais, Peter van Endert, Petros Giastas, Dieter W Hamprecht, Efstratios Stratikos

免疫/内分泌

发表日期：2024

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Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation

ERAP1和ERAP2能否形成功能性异二聚体？一项结构动力学研究

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2022.863529

Papakyriakou, Athanasios; Mpakali, Anastasia; Stratikos, Efstratios

发表日期：2022

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The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy

抗原加工和呈递在癌症中的作用以及免疫检查点抑制剂免疫疗法的疗效

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers13010134

Mpakali, Anastasia; Stratikos, Efstratios

The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I.

ERAP1 活性位点无法有效地接触稳定结合在 MHC I 类分子上的抗原肽前体的 N 端

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-021-95786-x

Mavridis George, Mpakali Anastasia, Zoidakis Jerome, Makridakis Manousos, Vlahou Antonia, Kaloumenou Eleni, Ziotopoulou Angeliki, Georgiadis Dimitris, Papakyriakou Athanasios, Stratikos Efstratios

发表日期：2021

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A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1

系统地重新检查内质网氨基肽酶 1 对 MHCI 结合抗原肽前体的加工

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA120.012976

George Mavridis, Richa Arya, Alexander Domnick, Jerome Zoidakis, Manousos Makridakis, Antonia Vlahou, Anastasia Mpakali, Angelos Lelis, Dimitris Georgiadis, Robert Tampé, Athanasios Papakyriakou, Lawrence J Stern, Efstratios Stratikos

信号转导

发表日期：2020

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Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

使用内质网氨基肽酶 1 (ERAP1) 的强效抑制剂编辑黑色素瘤细胞的免疫肽组

期刊:Cancer Immunology Immunotherapy

影响因子:8.1

doi:10.1007/s00262-019-02358-0

Despoina Koumantou, Eilon Barnea, Adrian Martin-Esteban, Zachary Maben, Athanasios Papakyriakou, Anastasia Mpakali, Paraskevi Kokkala, Harris Pratsinis, Dimitris Georgiadis, Lawrence J Stern, Arie Admon, Efstratios Stratikos

Molecular pathways for antigenic peptide generation by ER aminopeptidase 1

内质网氨肽酶1生成抗原肽的分子途径

期刊:Molecular Immunology

影响因子:3

doi:10.1016/j.molimm.2018.03.026

Mpakali, Anastasia; Maben, Zachary; Stern, Lawrence J; Stratikos, Efstratios

发表日期：2019

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Dnmt3a1 upregulates transcription of distinct genes and targets chromosomal gene clusters for epigenetic silencing in mouse embryonic stem cells

Dnmt3a1 上调不同基因的转录，并靶向染色体基因簇，在小鼠胚胎干细胞中实现表观遗传沉默

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.01093-10

Andriana G Kotini, Anastasia Mpakali, Theodora Agalioti

Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines

通过二芳基羟胺的结构修饰调节IDO1和TDO抑制作用

Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

ER 氨基肽酶 1 的自身免疫保护同种型 10 的多态性位置 349 和 725 是决定其独特酶特性的关键

Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor

新型底物选择性小分子抑制剂对胰岛素调节氨基肽酶开放构象的稳定

Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation

ERAP1和ERAP2能否形成功能性异二聚体？一项结构动力学研究

The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy

抗原加工和呈递在癌症中的作用以及免疫检查点抑制剂免疫疗法的疗效

The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I.

ERAP1 活性位点无法有效地接触稳定结合在 MHC I 类分子上的抗原肽前体的 N 端

A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1

系统地重新检查内质网氨基肽酶 1 对 MHCI 结合抗原肽前体的加工

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

使用内质网氨基肽酶 1 (ERAP1) 的强效抑制剂编辑黑色素瘤细胞的免疫肽组

Molecular pathways for antigenic peptide generation by ER aminopeptidase 1

内质网氨肽酶1生成抗原肽的分子途径

Dnmt3a1 upregulates transcription of distinct genes and targets chromosomal gene clusters for epigenetic silencing in mouse embryonic stem cells

Dnmt3a1 上调不同基因的转录，并靶向染色体基因簇，在小鼠胚胎干细胞中实现表观遗传沉默