日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

应用肝细胞色素 b5/P450 还原酶缺失 (HBRN) 小鼠研究细胞色素 b5 在细胞色素 P450 介导的抗癌药物玫瑰树碱生物活化中的作用

Lindsay Reed, Radek Indra, Iveta Mrizova, Michaela Moserova, Heinz H Schmeiser, C Roland Wolf, Colin J Henderson, Marie Stiborova, David H Phillips, Volker M Arlt

The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells

化疗药物对环境致癌物苯并[a]芘 CYP1A1 催化代谢的影响:对人类结直肠癌 HCT116 TP53(+/+)、TP53(+/-) 和 TP53(-/-) 细胞的影响

Alexandra J Willis, Radek Indra, Laura E Wohak, Osman Sozeri, Kerstin Feser, Iveta Mrizova, David H Phillips, Marie Stiborova, Volker M Arlt

Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice

细胞色素 b 5 对细胞色素 P450 介导的苯并[a]芘代谢及其 DNA 加合物形成的影响:在肝细胞色素 b 5 /P450 还原酶缺失 (HBRN) 小鼠中进行的研究

Lindsay Reed, Iveta Mrizova, Frantisek Barta, Radek Indra, Michaela Moserova, Klaus Kopka, Heinz H Schmeiser, C Roland Wolf, Colin J Henderson, Marie Stiborova, David H Phillips, Volker M Arlt

Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone

SULT1A 酶的基因调控对马兜铃酸和 3-硝基苯并蒽酮形成 DNA 加合物的影响

Volker M Arlt, Walter Meinl, Simone Florian, Eszter Nagy, Frantisek Barta, Marlies Thomann, Iveta Mrizova, Annette M Krais, Maggie Liu, Meirion Richards, Amin Mirza, Klaus Kopka, David H Phillips, Hansruedi Glatt, Marie Stiborova, Heinz H Schmeiser

Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

致癌空气污染物苯并[a]芘诱导的CYP1A1介导的呼吸道DNA损伤的肺部炎症影响

Arlt, Volker M; Krais, Annette M; Godschalk, Roger W; Riffo-Vasquez, Yanira; Mrizova, Iveta; Roufosse, Candice A; Corbin, Charmaine; Shi, Quan; Frei, Eva; Stiborova, Marie; van Schooten, Frederik-Jan; Phillips, David H; Spina, Domenico