Aryl-4,5-dihydro-1 H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII

带有磺酰胺部分的芳基-4,5-二氢-1 H-吡唑-1-甲酰胺衍生物对肿瘤相关的人类碳酸酐酶 IX 和 XII 表现出个位数纳摩尔至亚纳摩尔抑制常数