日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites.

对 SARS-CoV-2 RNA-蛋白质相互作用进行全基因组分析,揭示隐藏的调控位点

Xiang Joy S, Zhao Karen X, Tadri Laliv, Tamaru Kurt, Yee Brian A, Rothamel Katherine, Schmok Jonathan C, Mueller Jasmine R, Park Samuel S, Madrigal Assael A, McVicar Rachael N, Kwong Elizabeth M, Croker Ben A, Clark Alex E, Carlin Aaron F, Acevedo Charly, McCole Declan, O'Leary Seán E, Hai Rong, Leibel Sandra L, Yeo Gene W

Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes.

RNA剪接抑制会触发CHMP7进入细胞核,影响TDP-43的功能,从而导致ALS细胞表型的出现

Al-Azzam Norah, To Jenny H, Gautam Vaishali, Street Lena A, Nguyen Chloe B, Naritomi Jack T, Lam Dylan C, Madrigal Assael A, Lee Benjamin, Jin Wenhao, Avina Anthony, Mizrahi Orel, Mueller Jasmine R, Ford Willard, Schiavon Cara R, Rebollo Elena, Vu Anthony Q, Blue Steven M, Madakamutil Yashwin L, Manor Uri, Rothstein Jeffrey D, Coyne Alyssa N, Jovanovic Marko, Yeo Gene W