日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase

利用中子衍射技术从微重力条件下生长的晶体中揭示了色氨酸合酶内部醛亚胺形式的活性位点氢原子。

Drago, Victoria N; Devos, Juliette M; Blakeley, Matthew P; Forsyth, V Trevor; Parks, Jerry M; Kovalevsky, Andrey; Mueser, Timothy C

An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction

N⋯H⋯N 低势垒氢键预先组织天冬氨酸氨基转移酶的催化位点,以促进第二半反应。

Drago, Victoria N; Dajnowicz, Steven; Parks, Jerry M; Blakeley, Matthew P; Keen, David A; Coquelle, Nicolas; Weiss, Kevin L; Gerlits, Oksana; Kovalevsky, Andrey; Mueser, Timothy C

Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction

利用中子衍射技术在微重力条件下结晶全氘代色氨酸合酶

Drago, Victoria N; Devos, Juliette M; Blakeley, Matthew P; Forsyth, V Trevor; Kovalevsky, Andrey Y; Schall, Constance A; Mueser, Timothy C

Substrate Binding Stiffens Aspartate Aminotransferase by Altering the Enzyme Picosecond Vibrational Dynamics

底物结合通过改变酶的皮秒振动动力学使天冬氨酸氨基转移酶刚性增强

Dajnowicz, Steven; Cheng, Yongqiang; Daemen, Luke L; Weiss, Kevin L; Gerlits, Oksana; Mueser, Timothy C; Kovalevsky, Andrey

Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme

直接观察吡哆醛 5'-磷酸酶中的关键氢原子

Dajnowicz, Steven; Johnston, Ryne C; Parks, Jerry M; Blakeley, Matthew P; Keen, David A; Weiss, Kevin L; Gerlits, Oksana; Kovalevsky, Andrey; Mueser, Timothy C

Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.

直接证据表明,扩展的氢键网络会影响天冬氨酸氨基转移酶中磷酸吡哆醛的活化

Dajnowicz Steven, Parks Jerry M, Hu Xiche, Gesler Korie, Kovalevsky Andrey Y, Mueser Timothy C

Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state

可视化血红蛋白中的玻尔效应:马氰高铁血红蛋白在R态的中子结构及其与人脱氧血红蛋白在T态的比较

Dajnowicz, Steven; Seaver, Sean; Hanson, B Leif; Fisher, S Zoë; Langan, Paul; Kovalevsky, Andrey Y; Mueser, Timothy C

Thermodynamic and structural analysis of DNA damage architectures related to replication

与复制相关的DNA损伤结构的力学和结构分析

Amato, Nicholas J; Mwai, Christopher N; Mueser, Timothy C; Bryant-Friedrich, Amanda C

Models for the binary complex of bacteriophage T4 gp59 helicase loading protein: gp32 single-stranded DNA-BINDING protein and ternary complex with pseudo-Y junction DNA

噬菌体T4 gp59解旋酶装载蛋白与gp32单链DNA结合蛋白的二元复合物模型以及与假Y型连接DNA的三元复合物模型

Hinerman, Jennifer M; Dignam, J David; Mueser, Timothy C

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives

噬菌体T4 DNA复制的结构分析:噬菌体T4及其近缘种病毒学杂志系列综述

Mueser, Timothy C; Hinerman, Jennifer M; Devos, Juliette M; Boyer, Ryan A; Williams, Kandace J