日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TP53 mutation is associated with improved disease control in patients with advanced RAS wild-type colorectal adenocarcinoma treated with cetuximab and pembrolizumab

TP53 突变与接受西妥昔单抗和帕博利珠单抗治疗的晚期 RAS 野生型结直肠腺癌患者的疾病控制改善相关

Fountzilas, Christos; Rosario, Spencer; Witkiewicz, Agnieszka K; Withers, Henry G; Bajor, David L; Mukherjee, Sarbajit; Saltzman, Joel; Maguire, Orla; Minderman, Hans; Chatley, Sarah; Tarquini, Mary Lynn; Whitworth, Amy; Jurcevic, Jennifer; Hsiao, Hua-Hsin; Knudsen, Erik S; Muhitch, Jason B; Abrams, Scott I; Kalinski, Pawel; Segal, Brahm H; Bakin, Andrei; Yuan, Guangwei; Wang, Chong; Attwood, Kristopher; Iyer, Renuka; Boland, Patrick M

Stratification of Patients with Renal Cell Carcinoma by the Abundance of Sarcomatoid Features Reveals Differences in Survival and the Underlying Pathobiology

根据肉瘤样特征的丰富程度对肾细胞癌患者进行分层,揭示了生存率和潜在病理生物学方面的差异。

Salgia, Nicholas J; Aubrecht, Wilhelm M; Wang, Lin; Ram, Bebu; Wasik, Brianna J; Khan, Adil; Attwood, Kristopher; Daza, Jorge; Long, Mark D; Eng, Kevin H; Xu, Bo; Muhitch, Jason B; Kauffman, Eric C

Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.

将 IL-12 mRNA 纳米技术与 SBRT 相结合,可消除胰腺癌临床前模型中的 T 细胞耗竭

Hughson Angela L, Hannon Gary, Salama Noah A, Vrooman Tara G, Stockwell Caroline A, Mills Bradley N, Garrett-Larsen Jesse, Qiu Haoming, Katerji Roula, Benoodt Lauren, Johnston Carl J, Murphy Joseph D, Kruger Emma, Ye Jian, Gavras Nicholas W, Keeley David C, Qin Shuyang S, Lesch Maggie L, Muhitch Jason B, Love Tanzy M T, Calvi Laura M, Lord Edith M, Luheshi Nadia, Elyes Jim, Linehan David C, Gerber Scott A

Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis

铁沉积是肾细胞癌肿瘤发生的典型特征,但随着病理进展、肉瘤样去分化和转移而减轻。

Greene, Christopher J; Attwood, Kristopher; Sharma, Nitika J; Balderman, Benjamin; Deng, Rongia; Muhitch, Jason B; Smith, Gary J; Gross, Kenneth W; Xu, Bo; Kauffman, Eric C

Phase Ib/II Study of Cetuximab plus Pembrolizumab in Patients with Advanced RAS Wild-Type Colorectal Cancer

西妥昔单抗联合帕博利珠单抗治疗晚期 RAS 野生型结直肠癌患者的 Ib/II 期研究

Fountzilas, Christos; Bajor, David L; Mukherjee, Sarbajit; Saltzman, Joel; Witkiewicz, Agnieszka K; Maguire, Orla; Minderman, Hans; Nambiar, Ram; Rosenheck, Hanna R; Knudsen, Erik S; Muhitch, Jason B; Abrams, Scott I; Wang, Chong; Hutson, Alan D; Attwood, Kristopher; Hicks, Karen A; Jurcevic, Jennifer A; Kalinski, Pawel; Iyer, Renuka; Boland, Patrick M

Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients

辐射可诱导肾细胞癌患者T细胞库发生动态变化

Chow, Jacky; Hoffend, Nicholas C; Abrams, Scott I; Schwaab, Thomas; Singh, Anurag K; Muhitch, Jason B

Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

肿瘤相关巨噬细胞中干扰素调节因子-8 (IRF8) 的表达是肾细胞癌进展和患者生存的预测因子。

Muhitch, Jason B; Hoffend, Nicholas C; Azabdaftari, Gissou; Miller, Austin; Bshara, Wiam; Morrison, Carl D; Schwaab, Thomas; Abrams, Scott I

In situ thermal ablation augments antitumor efficacy of adoptive T cell therapy

原位热消融可增强过继性T细胞疗法的抗肿瘤疗效

Ito, Fumito; Vardam, Trupti D; Appenheimer, Michelle M; Eng, Kevin H; Gollnick, Sandra O; Muhitch, Jason B; Evans, Sharon S

Unmasking targets of antitumor immunity via high-throughput antigen profiling

通过高通量抗原分析揭示抗肿瘤免疫靶点

Battaglia, Sebastiano; Muhitch, Jason B

Preconditioning thermal therapy: flipping the switch on IL-6 for anti-tumour immunity

预处理热疗:激活IL-6以增强抗肿瘤免疫力

Mikucki, Maryann E; Fisher, Daniel T; Ku, Amy W; Appenheimer, Michelle M; Muhitch, Jason B; Evans, Sharon S