日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bridging the gap of axonal regeneration in the central nervous system: A state of the art review on central axonal regeneration

弥合中枢神经系统轴突再生的鸿沟:中枢轴突再生最新进展综述

Costa, Gonçalo; Ribeiro, Filipa F; Sebastião, Ana M; Muir, Elizabeth M; Vaz, Sandra H

Cerebellar plasticity and associative memories are controlled by perineuronal nets

小脑可塑性和联想记忆受神经元周围网状结构控制

Carulli, Daniela; Broersen, Robin; de Winter, Fred; Muir, Elizabeth M; Mešković, Maja; de Waal, Matthijs; de Vries, Sharon; Boele, Henk-Jan; Canto, Cathrin B; De Zeeuw, Chris I; Verhaagen, Joost

Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

免疫逃逸基因开关可实现脊髓损伤后软骨素酶的调控性递送

Burnside, Emily R; De Winter, Fred; Didangelos, Athanasios; James, Nicholas D; Andreica, Elena-Cristina; Layard-Horsfall, Hugo; Muir, Elizabeth M; Verhaagen, Joost; Bradbury, Elizabeth J

Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury.

移植产生软骨素酶 ABC 的犬嗅鞘细胞可促进脊髓损伤后硫酸软骨素蛋白聚糖的消化和轴突萌发

Carwardine Darren, Prager Jonathan, Neeves Jacob, Muir Elizabeth M, Uney James, Granger Nicolas, Wong Liang-Fong

Chondroitinase gene therapy improves upper limb function following cervical contusion injury

软骨素酶基因疗法可改善颈椎挫伤后的上肢功能

James, Nicholas D; Shea, Jessie; Muir, Elizabeth M; Verhaagen, Joost; Schneider, Bernard L; Bradbury, Elizabeth J

Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury.

利用软骨素酶基因疗法进行大规模硫酸软骨素蛋白聚糖消化,可减少脊髓挫伤后的病理变化并调节巨噬细胞表型

Bartus Katalin, James Nicholas D, Didangelos Athanasios, Bosch Karen D, Verhaagen Joost, Yáñez-Muñoz Rafael J, Rogers John H, Schneider Bernard L, Muir Elizabeth M, Bradbury Elizabeth J

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons.

慢病毒载体在皮质投射中表达软骨素酶ABC,促进受损皮质脊髓轴突的萌芽

Zhao Rong-Rong, Muir Elizabeth M, Alves João Nuno, Rickman Hannah, Allan Anna Y, Kwok Jessica C, Roet Kasper C D, Verhaagen Joost, Schneider Bernard L, Bensadoun Jean-Charles, Ahmed Sherif G, Yáñez-Muñoz Rafael J, Keynes Roger J, Fawcett James W, Rogers John H

Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells.

N-糖基化位点的修饰使得细菌软骨素酶ABC能够从哺乳动物细胞中分泌出来

Muir Elizabeth M, Fyfe Ian, Gardiner Sonya, Li Li, Warren Philippa, Fawcett James W, Keynes Roger J, Rogers John H