日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib

综合群体药代动力学、药效学和安全性分析，为ATR抑制剂Tuvusertib的临床开发中的剂量选择提供信息

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70029
Mukker, Jatinder Kaur; Diderichsen, Paul Matthias; Hellmann, Farina; Yap, Timothy A; Plummer, Ruth; Tolcher, Anthony W; de Bono, Johann S; Gounaris, Ioannis; Szucs, Zoltan; Zimmermann, Astrid; Kareva, Irina; Bolleddula, Jayaprakasam; Seithel-Keuth, Annick; Locatelli, Giuseppe; Enderlin, Marta; Hicking, Christine; Zutshi, Anup; Gao, Wei; Strotmann, Rainer; Benincosa, Lisa; Venkatakrishnan, Karthik
ATR
发表日期：2026
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Advancing Pharmacoequity Globally: Reflections from the ASCPT Development, Regulatory, and Outcomes Network

在全球范围内推进药物公平：来自ASCPT开发、监管和结果网络的思考

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70237
Jayachandran, Priya; Ladumor, Mayur K; Vlasakakis, Georgios; Riselli, Andrew; Ilic, Katarina V; van Wijk, Rob C; Elmeliegy, Mohamed; Mukker, Jatinder Kaur; Sawant-Basak, Aarti; Long, Tao; Dong, Juyao; Rayad, Noha; Zhang, Tao
ASC
发表日期：2026
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An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors

研究性ATRi药物Tuvusertib对实体瘤患者QTc间期影响的非临床和临床综合风险评估

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70496
Mukker, Jatinder Kaur; Yap, Timothy A; Tolcher, Anthony W; de Bono, Johann S; Plummer, Ruth; Grosser, Gary; van Amsterdam, Christoph; Schieferstein, Hanno; Witjes, Han; Diderichsen, Paul Matthias; Krebs-Brown, Axel; Gao, Wei; Strotmann, Rainer; Szucs, Zoltan; Gounaris, Ioannis; Venkatakrishnan, Karthik
ATR
发表日期：2026
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A First-in-Human Study of ATM Inhibitor Lartesertib as Monotherapy in Patients with Advanced Solid Tumors

一项针对晚期实体瘤患者的ATM抑制剂Lartesertib单药治疗的首次人体研究

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-1648
Siu, Lillian L; Yap, Timothy A; Genta, Sofia; Pennock, Gregory; Hicking, Christine; Vagge, Deepthi S; Mukker, Jatinder Kaur; Locatelli, Giuseppe; Tolcher, Anthony W
ATM
Human
发表日期：2025
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First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors

首次人体研究：毛细血管扩张性共济失调和Rad3相关（ATR）抑制剂Tuvusertib（M1774）作为单药疗法治疗实体瘤患者

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-23-2409
Yap, Timothy A; Tolcher, Anthony W; Plummer, Ruth; Mukker, Jatinder Kaur; Enderlin, Marta; Hicking, Christine; Grombacher, Thomas; Locatelli, Giuseppe; Szucs, Zoltan; Gounaris, Ioannis; de Bono, Johann S
ATR
Human
发表日期：2024
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Asia-inclusive drug development leveraging principles of ICH E5 and E17 guidelines: Case studies illustrating quantitative clinical pharmacology as a foundational enabler

以ICH E5和E17指南原则为基础，开展包容亚洲的药物研发：案例研究阐明定量临床药理学作为基础推动因素的作用

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70050
Lu, Hong; Klopp-Schulze, Lena; Mukker, Jatinder Kaur; Li, Dandan; Kuroki, Yoshihiro; Bolleddula, Jayaprakasam; Terranova, Nadia; Goteti, Kosalaram; Gao, Wei; Strotmann, Rainer; Dong, Jennifer; Venkatakrishnan, Karthik
发表日期：2024
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The pharmacokinetics of oral trazpiroben (TAK-906) after organic anion transporting polypeptide 1B1/1B3 inhibition: A phase I, randomized study

口服曲拉吡罗苯 (TAK-906) 在有机阴离子转运多肽 1B1/1B3 抑制后的药代动力学：一项 I 期随机研究

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.13274
Mukker, Jatinder K; Dukes, George; Tolkoff, Max; Wang, Lisi; Almansa, Cristina; Huh, Susanna Y; Nishihara, Mitsuhiro; Ramsden, Diane; Chen, Chunlin
发表日期：2022
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HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy

HOPX 在抗逆转录病毒药物诱导的表观遗传修饰和心脏肥大中起着关键作用

期刊:Cells
影响因子:5.1
doi:10.3390/cells10123458
Shiridhar Kashyap, Maryam Rabbani, Isabela de Lima, Olena Kondrachuk, Raj Patel, Mahnoush Sophia Shafiei, Avni Mukker, Aishwarya Rajakumar, Manish Kumar Gupta
微生物学
发表日期：2021
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Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation

抗逆转录病毒药物通过调节 H3K9 和 H3K27 乙酰化来调节心脏细胞的表观遗传修饰

期刊:Frontiers in Cardiovascular Medicine
影响因子:2.8
doi:10.3389/fcvm.2021.634774
Shiridhar Kashyap, Avni Mukker, Deepti Gupta, Prasun K Datta, Jay Rappaport, Jeffrey M Jacobson, Steven N Ebert, Manish K Gupta
表观遗传
其它细胞
发表日期：2021
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Clinical effectiveness of an acellular dermal regenerative tissue matrix compared to standard wound management in healing diabetic foot ulcers: a prospective, randomised, multicentre study

无细胞真皮再生组织基质与标准伤口处理方法治疗糖尿病足溃疡的临床疗效比较：一项前瞻性、随机、多中心研究

期刊:International Wound Journal
影响因子:2.5
doi:10.1111/j.1742-481X.2009.00585.x
Reyzelman, Alexander; Crews, Ryan T; Moore, John C; Moore, Lily; Mukker, Jagpreet S; Offutt, Stephen; Tallis, Arthur; Turner, William B; Vayser, Dean; Winters, Christopher; Armstrong, David G
糖尿病
细胞生物学
代谢
发表日期：2009
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