日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins.

无尾目石房蛤毒素结合蛋白对石房蛤毒素同系物结合和中和的结构基础

Zakrzewska Sandra, Nixon Samantha A, Chen Zhou, Hajare Holly S, Park Elizabeth R, Mulcahy John V, Arlinghaus Kandis M, Neu Eduard, Konovalov Kirill, Provasi Davide, Leighfield Tod A, Filizola Marta, Du Bois J, Minor Daniel L Jr

Discovery of Selective Inhibitors of Na(V)1.7 Templated on Saxitoxin as Therapeutics for Pain

以石房蛤毒素为模板发现选择性Na(V)1.7抑制剂作为疼痛治疗药物

Pajouhesh, Hassan; Delwig, Anton; Beckley, Jacob T; Klas, Sheri; Monteleone, Dennis; Zhou, Xiang; Luu, George; Du Bois, J; Hunter, John C; Mulcahy, John V

Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na(V)1.7

针对电压门控钠通道亚型Na(V)1.7的治疗面临的挑战与机遇

Mulcahy, John V; Pajouhesh, Hassan; Beckley, Jacob T; Delwig, Anton; Du Bois, J; Hunter, John C