日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

On the Utility of Infrared Photoactivation for Native Top-Down and Complex-Down Orbitrap Mass Spectrometry of Soluble Proteoform Complexes

红外光活化在可溶性蛋白质复合物的天然自上而下和复合物自下Orbitrap质谱分析中的应用

Nagy, Cynthia; Lieu, Linda B; Mullen, Christopher; McAlister, Graeme C; Melani, Rafael D; Hinkle, Joshua D; Fornelli, Luca

Native Mass Spectrometry-Based Proteomics Reveals the Mechanism of Hemophore Release by Pathogenic Corynebacterium diphtheriae

基于天然质谱的蛋白质组学揭示了致病性白喉棒状杆菌释放血红素的机制

Goring, Andrew K; Lyman, Lindsey R; Ford, Jordan; Huang, Jingjing; Mullen, Christopher; Melani, Rafael D; Schmitt, Michael P; Clubb, Robert T; Loo, Joseph A

Defining proteoform-specific interactions for drug targeting in a native cell signalling environment

在天然细胞信号传导环境中,确定蛋白质异构体特异性相互作用以进行药物靶向。

Lutomski, Corinne A; Bennett, Jack L; El-Baba, Tarick J; Wu, Di; Hinkle, Joshua D; Burnap, Sean A; Liko, Idlir; Mullen, Christopher; Syka, John E P; Struwe, Weston B; Robinson, Carol V

Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction

利用多重离子活化和质子转移电荷还原法对重组腺相关病毒衣壳蛋白进行自上而下的质谱分析

Kline, Jake T; Huang, Jingjing; Lieu, Linda B; Srzentić, Kristina; Bergen, David; Mullen, Christopher; McAlister, Graeme C; Durbin, Kenneth R; Melani, Rafael D; Fornelli, Luca

Enhanced Payload Localization in Antibody-Drug Conjugates Using a Middle-Down Mass Spectrometry Approach with Proton Transfer Charge Reduction

利用质子转移电荷还原的自下而上质谱方法增强抗体-药物偶联物中的有效载荷定位

Lieu, Linda B; Nagy, Cynthia; Huang, Jingjing; Mullen, Christopher; McAlister, Graeme C; Zabrouskov, Vlad; Srzentić, Kristina; Durbin, Kenneth R; Melani, Rafael D; Fornelli, Luca

Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy

患有 SCN2A 功能获得和丧失的发育性癫痫性脑病患者的 iPSC 衍生神经元具有独特的体外表型

Miaomiao Mao, Cristiana Mattei, Ben Rollo, Sean Byars, Claire Cuddy, Geza Berecki, Jacqueline Heighway, Svenja Pachernegg, Trevelyan Menheniott, Danielle Apted, Linghan Jia, Kelley Dalby, Alex Nemiroff, Saul Mullen, Christopher A Reid, Snezana Maljevic, Steven Petrou

Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction-Orbitrap mass spectrometry.

利用质子转移电荷还原-Orbitrap质谱法对抗体进行中层分析的通用方法

Oates Ryan N, Lieu Linda B, Kline Jake T, Mullen Christopher, Srzentić Kristina, Huguet Romain, McAlister Graeme C, Huang Jingjing, Bergen David, Melani Rafael D, Zabrouskov Vlad, Durbin Kenneth R, Syka John E P, Fornelli Luca

The genetic basis of conspicuous coloration in the Guadeloupean anole: Evolution by sexual and ecological selection

瓜德罗普岛蜥蜴显眼色彩的遗传基础:通过性和生态选择进化

Nicholas G Crawford, Thomas J McGreevy Jr, Sean P Mullen, Christopher J Schneider

Localised crystal-storing histiocytosis in a classical Hodgkin lymphoma patient post allogeneic transplant

异基因移植后经典型霍奇金淋巴瘤患者出现局部晶体储存组织细胞增生症

Kwon, Carol; Mullen, Christopher G; Buxton, Jennifer; AbuArqoub, Hadil

Development of JAK2 positive myelofibrosis on a background of chronic myeloid leukaemia

在慢性粒细胞白血病背景下发生JAK2阳性骨髓纤维化

Mullen, Christopher Gerard; Campbell, Victoria Louise; Doig, Tamasin; Klauser, Alice