日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer.

FGD3 介导细胞溶解性死亡,增强化疗药物在乳腺癌中的疗效和免疫原性。

Zhu Junyao, Dai Xinyi, Ghosh Santanu, Wei Elaine, Mao Chengjian, Jiang Qianjin, Spaulding Abigail J, Mulligan Michael P, Romero Roger, Han Yoo Jane, Boudreau Matthew W, Olopade Olufunmilayo, Hergenrother Paul J, Shapiro David J

Single Dose of a Small Molecule Leads to Complete Regressions of Large Breast Tumors in Mice

单次注射小分子药物可使小鼠体内大型乳腺肿瘤完全消退

Mulligan, Michael P; Boudreau, Matthew W; Bouwens, Brooke A; Lee, Yoongyeong; Carrell, Hunter W; Zhu, Junyao; Mousses, Spyro; Shapiro, David J; Nelson, Erik R; Fan, Timothy M; Hergenrother, Paul J

Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging.

利用单次定量相位梯度成像技术,以高时间分辨率捕捉细胞形态动态变化

Hur Sun Woong, Kwon Minsung, Manoharaan Revathi, Mohammadi Melika Haji, Samuel Ashok Zachariah, Mulligan Michael P, Hergenrother Paul J, Bhargava Rohit

An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections

迭代方法指导FabI抑制剂法比霉素的发现,法比霉素是一种后期抗生素候选药物,对耐药革兰氏阴性菌感染具有体内疗效。

Parker, Erica N; Cain, Brett N; Hajian, Behnoush; Ulrich, Rebecca J; Geddes, Emily J; Barkho, Sulyman; Lee, Hyang Yeon; Williams, John D; Raynor, Malik; Caridha, Diana; Zaino, Angela; Shekhar, Mrinal; Muñoz, Kristen A; Rzasa, Kara M; Temple, Emily R; Hunt, Diana; Jin, Xiannu; Vuong, Chau; Pannone, Kristina; Kelly, Aya M; Mulligan, Michael P; Lee, Katie K; Lau, Gee W; Hung, Deborah T; Hergenrother, Paul J

Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections"

对“迭代方法指导发现FabI抑制剂法比霉素,一种对耐药革兰氏阴性菌感染具有体内疗效的后期抗生素候选药物”一文的更正

Parker, Erica N; Cain, Brett N; Hajian, Behnoush; Ulrich, Rebecca J; Geddes, Emily J; Barkho, Sulyman; Lee, Hyang Yeon; Williams, John D; Raynor, Malik; Caridha, Diana; Zaino, Angela; Rohde, Jason M; Zak, Mark; Shekhar, Mrinal; Muñoz, Kristen A; Rzasa, Kara M; Temple, Emily R; Hunt, Diana; Jin, Xiannu; Vuong, Chau; Pannone, Kristina; Kelly, Aya M; Mulligan, Michael P; Lee, Katie K; Lau, Gee W; Hung, Deborah T; Hergenrother, Paul J

Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide

微管稳定剂(-)-zampanolide和(-)-dactylolide的构象类似物的合成、构象偏好和生物活性

Henry, Jeffrey L; Wilson, Matthew R; Mulligan, Michael P; Quinn, Taylor R; Sackett, Dan L; Taylor, Richard E