日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Matching heterogeneous cohorts by projected principal components reveals two novel Alzheimer's disease-associated genes in the Hispanic population

通过预测主成分匹配异质性队列，揭示了西班牙裔人群中两个新的阿尔茨海默病相关基因

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.71189
Willett, Julian Daniel Sunday; Waqas, Mohamad; Naumenko, Serhiy; Mullin, Kristina; Hecker, Julian; Bertram, Lars; Lange, Christoph; Vlachos, Ioannis; Hide, Winston; Tanzi, Rudolph E; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2026
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Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses

利用多祖先荟萃分析鉴定出16个新的阿尔茨海默病基因位点

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.14592
Willett, Julian Daniel Sunday; Waqas, Mohammad; Choi, Younjung; Ngai, Tiffany; Mullin, Kristina; Tanzi, Rudolph E; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2025
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A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer's disease.

PKCη错义突变增强了高尔基体定位的信号传导，并且与隐性遗传的家族性阿尔茨海默病有关

期刊:Science Signaling
影响因子:6.6
doi:10.1126/scisignal.adv0970
Gauron Maria Celeste, Prokopenko Dmitry, Lee Sanghun, Wolfe Sarah A, Hecker Julian, Willett Julian, Waqas Mohammad, Lordén Gema, Yang Yimin, Mayfield Joshua E, Castanho Isabel, Mullin Kristina, Morgan Sarah, Hahn Georg, Demeo Dawn L, Hide Winston, Bertram Lars, Lange Christoph, Newton Alexandra C, Tanzi Rudolph E
信号转导
发表日期：2025
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Matching Heterogeneous Cohorts by Projected Principal Components Reveals Two Novel Alzheimer's Disease-Associated Genes in the Hispanic Population

通过预测主成分匹配异质队列，揭示了西班牙裔人群中两个新的阿尔茨海默病相关基因

期刊:
影响因子:
doi:10.1101/2025.01.18.25320774
Willett, Julian Daniel Sunday; Waqas, Mohamad; Naumenko, Serhiy; Mullin, Kristina; Hecker, Julian; Bertram, Lars; Lange, Christoph; Vlachos, Ioannis; Hide, Winston; Tanzi, Rudolph E; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2025
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Protein kinase C eta enhances Golgi-localized signaling and is associated with Alzheimer's disease using a recessive mode of inheritance.

蛋白激酶 C eta 可增强高尔基体定位的信号传导，并以隐性遗传方式与阿尔茨海默病相关

期刊:
影响因子:
doi:10.1101/2025.05.13.25327562
Gauron Maria Celeste, Prokopenko Dmitry, Lee Sanghun, Wolfe Sarah A, Hecker Julian, Willett Julian, Waqas Mohammad, Lordén Gema, Yang Yimin, Mayfield Joshua E, Castanho Isabel, Mullin Kristina, Morgan Sarah, Hahn Georg, Demeo Dawn L, Hide Winston, Bertram Lars, Lange Christoph, Newton Alexandra C, Tanzi Rudolph E
免疫/内分泌
发表日期：2025
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On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries

不同遗传祖先中已确定的阿尔茨海默病易感基因位点异质性的影响

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.13796
Lee, Sanghun; Hecker, Julian; Hahn, Georg; Mullin, Kristina; Lutz, Sharon M; Tanzi, Rudolph E; Lange, Christoph; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2024
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Assessing polyomic risk to predict Alzheimer's disease using a machine learning model

利用机器学习模型评估多组学风险以预测阿尔茨海默病

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.14319
Ngai, Tiffany; Willett, Julian; Waqas, Mohammad; Fishbein, Lucas H; Choi, Younjung; Hahn, Georg; Mullin, Kristina; Lange, Christoph; Hecker, Julian; Tanzi, Rudolph E; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2024
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Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data

利用多组学数据协同学习预测精准医疗中的无病生存期

期刊:Briefings in Bioinformatics
影响因子:7.7
doi:10.1093/bib/bbae267
Hahn, Georg; Prokopenko, Dmitry; Hecker, Julian; Lutz, Sharon M; Mullin, Kristina; Sejour, Leinal; Hide, Winston; Vlachos, Ioannis; DeSantis, Stacia; Tanzi, Rudolph E; Lange, Christoph
发表日期：2024
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Identification of 16 novel Alzheimer's disease susceptibility loci using multi-ancestry meta-analyses of clinical Alzheimer's disease and AD-by-proxy cases from four whole genome sequencing datasets

利用来自四个全基因组测序数据集的临床阿尔茨海默病和代理阿尔茨海默病病例的多祖先荟萃分析，鉴定出16个新的阿尔茨海默病易感基因位点

期刊:
影响因子:
doi:10.1101/2024.09.11.24313439
Willett, Julian Daniel Sunday; Waqas, Mohammad; Choi, Younjung; Ngai, Tiffany; Mullin, Kristina; Tanzi, Rudolph E; Prokopenko, Dmitry
阿尔茨海默症
发表日期：2024
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A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets

对用于主成分分析的相似性矩阵进行比较，以评估测序遗传数据集中的群体分层

期刊:Briefings in Bioinformatics
影响因子:7.7
doi:10.1093/bib/bbac611
Lee, Sanghun; Hahn, Georg; Hecker, Julian; Lutz, Sharon M; Mullin, Kristina; Hide, Winston; Bertram, Lars; DeMeo, Dawn L; Tanzi, Rudolph E; Lange, Christoph; Prokopenko, Dmitry
发表日期：2023
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