日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineering multispecific antibodies with complete killing selectivity through the closed-loop integration of machine learning and high-throughput experimentation

通过机器学习和高通量实验的闭环整合,设计具有完全杀伤选择性的多特异性抗体

Grace, Justin; Colin, Pierre-Yves; Foxler, Dan; Haynes, Winston; Howsham, Catherine; Kassimatis, Leo; Mavrogonatou, Lida; Mighell, Rebecca; McClory, James; Mullin, Michael; Ogola, Tom; Townsend, Alex; Ravi, Sujata; Wossnig, Leo; van Heeke, Gino

Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions

基于VHH的双特异性抗体设计中的应用与挑战:利用机器学习解决方案

Mullin, Michael; McClory, James; Haynes, Winston; Grace, Justin; Robertson, Nathan; van Heeke, Gino

Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines

抗体-蛋白水解靶向嵌合偶联物可选择性降解HER2+细胞系中的受体相互作用丝氨酸/苏氨酸蛋白激酶2

Chan, Karina; Sathyamurthi, Preethi Soundarya; Queisser, Markus A; Mullin, Michael; Shrives, Harry; Coe, Diane M; Burley, Glenn A

Xeno-Free Reprogramming of Peripheral Blood Mononuclear Erythroblasts on Laminin-521

外周血单核红细胞在层粘连蛋白-521 上的无异种重编程

Christian Skorik, Nathaniel K Mullin, Michael Shi, Yosra Zhang, Phoebe Hunter, Yang Tang, Brianna Hilton, Thorsten M Schlaeger

CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.

CEP192 与 K63 去泛素化酶 CYLD 发生物理和功能上的相互作用,从而促进有丝分裂纺锤体的组装

Gomez-Ferreria Maria Ana, Bashkurov Mikhail, Mullin Michael, Gingras Anne-Claude, Pelletier Laurence

Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5.

无标记定量蛋白质组学和 SAINT 分析能够绘制人类 Ser/Thr 蛋白磷酸酶 5 的相互作用组图谱

Skarra Dana V, Goudreault Marilyn, Choi Hyungwon, Mullin Michael, Nesvizhskii Alexey I, Gingras Anne-Claude, Honkanen Richard E

Improvement of postprandial endothelial function after a single dose of exenatide in individuals with impaired glucose tolerance and recent-onset type 2 diabetes

单次注射艾塞那肽后,葡萄糖耐量受损和新发2型糖尿病患者的餐后内皮功能得到改善

Koska, Juraj; Schwartz, Eric A; Mullin, Michael P; Schwenke, Dawn C; Reaven, Peter D