PPT1 is a negative regulator of STING signaling in cancer cells and its inhibition reactivates immune surveillance in cold tumors
PPT1是癌细胞中STING信号的负调控因子，抑制PPT1可以重新激活冷肿瘤中的免疫监视功能。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2514948122
Chowdhury, Shreya R; Parikh, Chaitanya N; Kaur, Arshia N; DeMarco, Kelly D; Giwa, Hadiya K; Mishra, Alok K; Murphy, Katherine C; Zhou, Lin; Ma, Boyang; Ye, Tianyi; Li, Junhui; Liu, Haibo; Bai, Shi; Johnson, Calvin; Simin, Karl; Pitarresi, Jason R; Zhu, Lihua Julie; Watson, Emma V; Kelliher, Michelle A; Green, Michael R; Fitzgerald, Katherine A; Ruscetti, Marcus
信号转导
免疫/内分泌
细胞生物学
STING
肿瘤
肿瘤免疫
