日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

通过增强革兰氏阴性菌中二氢蝶酸合成酶蝶呤结合位点的全细胞靶向结合来开发嘧啶并哒嗪类似物

Snoke, Hannah E; Reeve, Stephanie M; Dharuman, Suresh; Wallace, Miranda J; Loudon, Victoria C; Zhao, Ying; Bowling, John J; Murphy, Patricia A; Waddell, Brett; Lee, Robin B; Bulitta, Jürgen B; Lee, Richard E

Development of tetracycline analogues with increased aqueous stability for the treatment of mycobacterial infections.

开发具有更高水稳定性的四环素类似物用于治疗分枝杆菌感染

Liu Jiuyu, Phelps Gregory A, Dunn Christine M, Murphy Patricia A, Wilt Laura A, Loudon Victoria, Lee Robin B, Fernando Dinesh, Yang Lei, Tran Kristina N, Troyer Brennen T, Obregon-Henao Andres, Lee Richard E

Correction: Synthesis and antibacterial action of 3',6'-disubstituted spectinomycins

更正:3',6'-二取代壮观霉素的合成及其抗菌作用

Dharuman, Suresh; Phelps, Gregory A; Dunn, Christine M; Wilt, Laura A; Murphy, Patricia A; Lee, Robin B; Snoke, Hannah E; Selchow, Petra; Haldimann, Klara; Böttger, Erik C; Hobbie, Sven N; Sander, Peter; Lee, Richard E

Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice

口服夏枯草提取物可减轻 mdr1a(-/-) 小鼠的自发性结肠炎

Haarberg, Kelley Mk; Wymore Brand, Meghan J; Overstreet, Anne-Marie C; Hauck, Catherine C; Murphy, Patricia A; Hostetter, Jesse M; Ramer-Tait, Amanda E; Wannemuehler, Michael J

Effect of chronic lead intoxication on the distribution and elimination of amoxicillin in goats

慢性铅中毒对山羊体内阿莫西林分布和消除的影响

Soliman, Ahmed M; Abu-Basha, Ehab A; Youssef, Salah A H; Amer, Aziza M; Murphy, Patricia A; Hauck, Catherine C; Gehring, Ronette; Hsu, Walter H

Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae

不同的活性氧物种会导致真核模式生物酿酒酵母细胞内金属离子发生不同的变化。

Wu, Ming J; O'Doherty, Patrick J; Murphy, Patricia A; Lyons, Victoria; Christophersen, Melinda; Rogers, Peter J; Bailey, Trevor D; Higgins, Vincent J

Identification of anti-inflammatory constituents in Hypericum perforatum and Hypericum gentianoides extracts using RAW 264.7 mouse macrophages

利用 RAW 264.7 小鼠巨噬细胞鉴定贯叶连翘和龙胆金丝桃提取物中的抗炎成分

Huang, Nan; Rizshsky, Ludmila; Hauck, Cathy; Nikolau, Basil J; Murphy, Patricia A; Birt, Diane F

Echinacea increases arginase activity and has anti-inflammatory properties in RAW 264.7 macrophage cells, indicative of alternative macrophage activation

紫锥菊可提高RAW 264.7巨噬细胞中精氨酸酶的活性,并具有抗炎特性,这表明其可激活巨噬细胞的另一种途径。

Zhai, Zili; Solco, Avery; Wu, Lankun; Wurtele, Eve S; Kohut, Marian L; Murphy, Patricia A; Cunnick, Joan E

Hypericum in infection: Identification of anti-viral and anti-inflammatory constituents

贯叶连翘在感染中的应用:抗病毒和抗炎成分的鉴定

Birt, Diane F; Widrlechner, Mark P; Hammer, Kimberly Dp; Hillwig, Matthew L; Wei, Jingqiang; Kraus, George A; Murphy, Patricia A; McCoy, Joeann; Wurtele, Eve S; Neighbors, Jeffrey D; Wiemer, David F; Maury, Wendy J; Price, Jason P

Reduction in hypericin-induced phototoxicity by Hypericum perforatum extracts and pure compounds.

贯叶连翘提取物和纯化合物可降低金丝桃素诱导的光毒性

Schmitt Laura A, Liu Yi, Murphy Patricia A, Petrich Jacob W, Dixon Philip M, Birt Diane F