日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Balancing brain exposure, pharmacokinetics and safety of transferrin receptor antibodies for delivery of neuro-therapeutics

平衡转铁蛋白受体抗体在神经治疗药物递送中的脑暴露、药代动力学和安全性

Smith, Benjamin A; Meeks, Caitlin B; Murray-Brown, Isabel; McCarthy, Elizabeth A; Julian, Mark C; Arndt, Joe; Stewart, Matthew; Spilker, Kerri; D'Lima, Nadia; Dolnikova, Jana; Li, You; Prasad, Shikha; Qian, Fang; Gong, BangJian; Jiang, Di; Yuan, Long; Tuczkewycz, Taras; Amatucci, Joseph; Doyle, Rachel; Wagatsuma, Akiko; Yang, Fu-Chia; Pepinsky, Blake; Weinreb, Paul H; Cameron, Thomas O; Koksal, Adem C

Transcriptomic profiling of programmed cell death 1 (PD-1) expressing T cells in early rheumatoid arthritis identifies a decreased CD4 + PD-1 + signature post-treatment

早期类风湿关节炎中表达程序性细胞死亡 1 (PD-1) 的 T 细胞的转录组分析显示治疗后 CD4 + PD-1 + 特征减少

Katie Lowe, Annabelle Small, Qingxuan Song, Ling-Yang Hao, William Murray-Brown, Susanna Proudman, Malcolm D Smith, Sunil Nagpal, Mihir D Wechalekar

Differential expansion of T peripheral helper cells in early rheumatoid arthritis and osteoarthritis synovium

早期类风湿关节炎和骨关节炎滑膜中T外周辅助细胞的差异性扩增

William Murray-Brown, Yanxia Guo, Annabelle Small, Katie Lowe, Helen Weedon, Malcolm D Smith, Susan E Lester, Susanna M Proudman, Navin L Rao, Ling-Yang Hao, Sunil Nagpal, Mihir D Wechalekar

SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders

SARS-CoV-2介导的神经炎症及COVID-19对神经系统疾病的影响

Amruta, Narayanappa; Chastain, Wesley H; Paz, Meshi; Solch, Rebecca J; Murray-Brown, Isabel C; Befeler, Jaime B; Gressett, Timothy E; Longo, Michele T; Engler-Chiurazzi, Elizabeth B; Bix, Gregory

Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin

开发一种可纠正错误折叠并增加 Z α1 -抗胰蛋白酶分泌的小分子

David A Lomas, James A Irving, Christopher Arico-Muendel, Svetlana Belyanskaya, Andrew Brewster, Murray Brown, Chun-Wa Chung, Hitesh Dave, Alexis Denis, Nerina Dodic, Anthony Dossang, Peter Eddershaw, Diana Klimaszewska, Imran Haq, Duncan S Holmes, Jonathan P Hutchinson, Alistair M Jagger, Toral Jak

In Vivo protection from SARS-CoV-2 infection by ATN-161 in k18-hACE2 transgenic mice

ATN-161 在 k18-hACE2 转基因小鼠体内保护小鼠免受 SARS-CoV-2 感染

Narayanappa Amruta, Elizabeth B Engler-Chiurazzi, Isabel C Murray-Brown, Timothy E Gressett, Ifechukwude J Biose, Wesley H Chastain, Jaime B Befeler, Gregory Bix

Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma

在 ICOS 控制下,IL-21+ Tfh 和 Tph 细胞的独特扩增可识别伴有异位生发中心和 MALT 淋巴瘤的干燥综合征

Elena Pontarini #, William James Murray-Brown #, Cristina Croia #, Davide Lucchesi, James Conway, Felice Rivellese, Liliane Fossati-Jimack, Elisa Astorri, Edoardo Prediletto, Elisa Corsiero, Francesca Romana Delvecchio, Rachel Coleby, Eva Gelbhardt, Aurora Bono, Chiara Baldini, Ilaria Puxeddu, Piero

Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy

纳武利尤单抗诱发的滑膜炎以T细胞大量浸润为特征,并在滑膜活检指导治疗下迅速消退。

Murray-Brown, William; Wilsdon, Tom D; Weedon, Helen; Proudman, Susanna; Sukumaran, Shawgi; Klebe, Sonja; Walker, Jennifer G; Smith, Malcolm D; Wechalekar, Mihir D

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

全基因组关联分析确定TXNRD2、ATXN2和FOXC1是原发性开角型青光眼的易感基因位点

Bailey, Jessica N Cooke; Loomis, Stephanie J; Kang, Jae H; Allingham, R Rand; Gharahkhani, Puya; Khor, Chiea Chuen; Burdon, Kathryn P; Aschard, Hugues; Chasman, Daniel I; Igo, Robert P Jr; Hysi, Pirro G; Glastonbury, Craig A; Ashley-Koch, Allison; Brilliant, Murray; Brown, Andrew A; Budenz, Donald L; Buil, Alfonso; Cheng, Ching-Yu; Choi, Hyon; Christen, William G; Curhan, Gary; De Vivo, Immaculata; Fingert, John H; Foster, Paul J; Fuchs, Charles; Gaasterland, Douglas; Gaasterland, Terry; Hewitt, Alex W; Hu, Frank; Hunter, David J; Khawaja, Anthony P; Lee, Richard K; Li, Zheng; Lichter, Paul R; Mackey, David A; McGuffin, Peter; Mitchell, Paul; Moroi, Sayoko E; Perera, Shamira A; Pepper, Keating W; Qi, Qibin; Realini, Tony; Richards, Julia E; Ridker, Paul M; Rimm, Eric; Ritch, Robert; Ritchie, Marylyn; Schuman, Joel S; Scott, William K; Singh, Kuldev; Sit, Arthur J; Song, Yeunjoo E; Tamimi, Rulla M; Topouzis, Fotis; Viswanathan, Ananth C; Verma, Shefali Setia; Vollrath, Douglas; Wang, Jie Jin; Weisschuh, Nicole; Wissinger, Bernd; Wollstein, Gadi; Wong, Tien Y; Yaspan, Brian L; Zack, Donald J; Zhang, Kang; Study, Epic-Norfolk Eye; Weinreb, Robert N; Pericak-Vance, Margaret A; Small, Kerrin; Hammond, Christopher J; Aung, Tin; Liu, Yutao; Vithana, Eranga N; MacGregor, Stuart; Craig, Jamie E; Kraft, Peter; Howell, Gareth; Hauser, Michael A; Pasquale, Louis R; Haines, Jonathan L; Wiggs, Janey L

Haloperidol for the treatment of nausea and vomiting in palliative care patients

氟哌啶醇用于治疗姑息治疗患者的恶心和呕吐

Murray-Brown, Fay; Dorman, Saskie