日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IPH5201, an Anti-CD39 mAb, as Monotherapy or in Combination with Durvalumab in Advanced Solid Tumors

IPH5201,一种抗CD39单克隆抗体,可作为单药疗法或与度伐利尤单抗联合用于治疗晚期实体瘤。

Powderly, John; Imbimbo, Martina; Italiano, Antoine; Martin-Romano, Patricia; McKean, Meredith; Macarulla, Teresa; Castañón Alvarez, Eduardo; Carneiro, Benedito A; Mager, Raymond; Barnhart, Vicky; Eck, Steven; Murtomaki, Elina; Loembé, Arsène-Bienvenu; He, Yun; Cooper, Zachary A; Tu, Eric; Fan, Chunling; Boyer Chamard, Agnes; Paturel, Carine; Fraenkel, Paula G; Hollebecque, Antoine

A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

一项针对转移性胰腺导管腺癌患者的Ib/II期随机临床试验,评估奥莱克鲁单抗联合或不联合度伐利尤单抗及化疗的疗效

Coveler, Andrew L; Reilley, Matthew J; Zalupski, Mark; Macarulla, Teresa; Fountzilas, Christos; Ponz-Sarvisé, Mariano; Nagrial, Adnan; Uboha, Nataliya V; Frentzas, Sophia; Overman, Michael; Noonan, Anne; Messersmith, Wells A; Pavlakis, Nick; Mettu, Niharika B; Bisha, Ina; Wang, Ying; Smith, Paul; Murtomaki, Elina; Bielska, Agata A; Bragulat, Veronique; Cooper, Zachary A; Kumar, Rakesh; Spigel, David R

Unique functions for Notch4 in murine embryonic lymphangiogenesis

Notch4在小鼠胚胎淋巴管生成中的独特功能

Muley, Ajit; Kim Uh, Minji; Salazar-De Simone, Glicella; Swaminathan, Bhairavi; James, Jennifer M; Murtomaki, Aino; Youn, Seock Won; McCarron, Joseph D; Kitajewski, Chris; Gnarra Buethe, Maria; Riitano, Gloria; Mukouyama, Yoh-Suke; Kitajewski, Jan; Shawber, Carrie J

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth

选择性阻断 DLL/NOTCH 或 JAG/NOTCH 的 NOTCH 诱饵通过独特的机制破坏血管生成,从而抑制肿瘤生长。

Kangsamaksin, Thaned; Murtomaki, Aino; Kofler, Natalie M; Cuervo, Henar; Chaudhri, Reyhaan A; Tattersall, Ian W; Rosenstiel, Paul E; Shawber, Carrie J; Kitajewski, Jan

Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium

Notch1 在静脉内皮中起淋巴管内皮细胞分化的负调节作用

Aino Murtomaki, Minji K Uh, Yun K Choi, Christopher Kitajewski, Valeriya Borisenko, Jan Kitajewski, Carrie J Shawber

NOTCH2 expression is decreased in epithelial ovarian cancer and is related to the tumor histological subtype

NOTCH2 在上皮性卵巢癌中表达降低,且与肿瘤组织学亚型相关

Vijaya Galic, Carrie J Shawber, Claire Reeves, Monjri Shah, Aino Murtomaki, Jason Wright, Thomas Herzog, Guo Xia Tong, Jan Kitajewski

Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT Study Invsestigators

肝脂肪酶活性变异与肝脂肪酶基因启动子变异的关联。LOCAT 研究调查员

Tahvanainen, E; Syvanne, M; Frick, M H; Murtomaki-Repo, S; Antikainen, M; Kesaniemi, Y A; Kauma, H; Pasternak, A; Taskinen, M R; Ehnholm, C