日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Heterologous betacoronavirus spike immunization in nonhuman primates elicits cross-reactive antibodies that neutralize both sarbeco- and merbecoviruses.

在非人灵长类动物中进行异源β冠状病毒刺突蛋白免疫可诱导产生交叉反应抗体,该抗体可中和沙贝病毒和默贝病毒。

Dueker Katharina, Capozzola Tazio, Feng Ziqi, Lin Ryan N, Hurtado Jonathan, Bangaru Sandhya, Yuan Meng, Beutler Nathan, Garcia Elijah, He Wan-Ting, Callaghan Sean, Avillion Gabriel, Vo Lina, Li Xuduo, Torres Jonathan L, Musharrafieh Rami, Song Ge, Mishra Nitesh, Sharma Pragati, Yong Peter, Anzanello Fabio, Kaczmarek-Michaels Kasia, Ben-Akiva Elana, Silva Murillo, Melo Mariane, Makhdoomi Muzamil, Westfall-Gomez Ethan, Rinaldi William, Ferguson Melissa, Safonova Yana, Crotty Shane, Irvine Darrell J, Rogers Thomas, Ward Andrew B, Briney Bryan, Wilson Ian A, Burton Dennis R, Andrabi Raiees

Development of broad-spectrum enterovirus antivirals based on quinoline scaffold

基于喹啉骨架的广谱肠道病毒抗病毒药物的开发

Musharrafieh, Rami; Kitamura, Naoya; Hu, Yanmei; Wang, Jun

Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments

通过生物分子模拟和病毒传代实验研究M2-S31N通道阻滞剂的耐药机制

Musharrafieh, Rami; Lagarias, Panagiotis; Ma, Chunlong; Hau, Raymond; Romano, Alex; Lambrinidis, George; Kolocouris, Antonios; Wang, Jun

In Vitro Pharmacokinetic Optimizations of AM2-S31N Channel Blockers Led to the Discovery of Slow-Binding Inhibitors with Potent Antiviral Activity against Drug-Resistant Influenza A Viruses.

AM2-S31N 通道阻滞剂的体外药代动力学优化发现了对耐药性甲型流感病毒具有强效抗病毒活性的慢结合抑制剂

Wang Yuanxiang, Hu Yanmei, Xu Shuting, Zhang Yongtao, Musharrafieh Rami, Hau Raymond Kin, Ma Chunlong, Wang Jun

Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers

分析甲型流感病毒对AM2-S31N质子通道阻滞剂的体外耐药机制

Musharrafieh, Rami; Ma, Chunlong; Wang, Jun

Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral

化学基因组学方法鉴定出橙皮苷(一种 Aurora B 激酶抑制剂)是一种广谱流感抗病毒药物

Hu, Yanmei; Zhang, Jiantao; Musharrafieh, Rami; Hau, Raymond; Ma, Chunlong; Wang, Jun

Effects of transportation stress and addition of salt to transport water on the skin mucosal homeostasis of rainbow trout (Oncorhynchus mykiss)

运输应激和向运输水中添加盐分对虹鳟(Oncorhynchus mykiss)皮肤粘膜稳态的影响

Tacchi, Luca; Lowrey, Liam; Musharrafieh, Rami; Crossey, Kyle; Larragoite, Erin T; Salinas, Irene