日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome

MIDEAS基因中的一种新发错义突变导致MiDAC HDAC复合物的去乙酰化酶活性增强，从而引起神经发育综合征。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65472-x
Fairall, Louise; Sirvydis, Kristupas; Turnbull, Robert E; Knottnerus, Suzan Jg; Gonchar, Oksana; Muskett, Frederick W; Jukes-Jones, Rebekah; van Brussel, Lonneke; van de Geer, Ellen; van Gassen, Koen; Badenhorst, Paul; Johnson, Diana; Terhal, Paulien A; van Hasselt, Peter M; van Jaarsveld, Richard H; Schwabe, John Wr
表观遗传
神经科学
乙酰化
发育与干细胞
IDE
发表日期：2025
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2'-(19)F labelling of ribose in RNAs: a tool to analyse RNA/protein interactions by NMR in physiological conditions

RNA中核糖的2'-(19)F标记：一种在生理条件下利用核磁共振分析RNA/蛋白质相互作用的工具

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2024.1325041
Kara, Hesna; Axer, Alexander; Muskett, Frederick W; Bueno-Alejo, Carlos J; Paschalis, Vasileios; Taladriz-Sender, Andrea; Tubasum, Sumera; Vega, Marina Santana; Zhao, Zhengyun; Clark, Alasdair W; Hudson, Andrew J; Eperon, Ian C; Burley, Glenn A; Dominguez, Cyril
发表日期：2024
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Characterizing the protein-protein interaction between MDM2 and 14-3-3σ; proof of concept for small molecule stabilization

表征MDM2和14-3-3σ之间的蛋白质-蛋白质相互作用；小分子稳定化的概念验证

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2024.105651
Ward, Jake A; Romartinez-Alonso, Beatriz; Kay, Danielle F; Bellamy-Carter, Jeddidiah; Thurairajah, Bethany; Basran, Jaswir; Kwon, Hanna; Leney, Aneika C; Macip, Salvador; Roversi, Pietro; Muskett, Frederick W; Doveston, Richard G
MDM2
发表日期：2024
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N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells

N-酰氧基甲基邻苯二甲酰亚胺可将具有基因毒性的甲醛输送至人体细胞。

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d3sc02867d
Emms, Vicki L; Lewis, Liam A; Beja, Lilla; Bulman, Natasha F A; Pires, Elisabete; Muskett, Frederick W; McCullagh, James S O; Swift, Lonnie P; McHugh, Peter J; Hopkinson, Richard J
细胞生物学
毒理研究
发表日期：2023
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Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism.

IL-17骨架动力学的调节降低了受体亲和力，揭示了一种新的抑制机制

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d3sc00728f
Shaw Daniel J, Waters Lorna C, Strong Sarah L, Schulze Monika-Sarah E D, Greetham Gregory M, Towrie Mike, Parker Anthony W, Prosser Christine E, Henry Alistair J, Lawson Alastair D G, Carr Mark D, Taylor Richard J, Hunt Neil T, Muskett Frederick W
骨科研究
发表日期：2023
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Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80

鉴定、结合和结构表征抑制免疫调节蛋白PD-1和CD80的单域抗PD-L1抗体

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2022.102769
Kang-Pettinger, Tara; Walker, Kayleigh; Brown, Richard; Cowan, Richard; Wright, Helena; Baravalle, Roberta; Waters, Lorna C; Muskett, Frederick W; Bowler, Matthew W; Sawmynaden, Kovilen; Coombs, Peter J; Carr, Mark D; Hall, Gareth
T细胞
CD8
免疫/内分泌
PD-L1
PD-1
CD80
发表日期：2023
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Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation

Bcl-x前体mRNA的生物物理特性及椭圆吡啶衍生物GQC-05的结合特异性：对选择性剪接调控的启示

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2022.943105
Bhogadia, Mohammed; Stone, Beth; Del Villar Guerra, Rafael; Muskett, Frederick W; Ghosh, Sudipta; Taladriz-Sender, Andrea; Burley, Glenn A; Eperon, Ian C; Hudson, Andrew J; Dominguez, Cyril
信号转导
发表日期：2022
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Sequence-specific (1)H, (13)C and (15)N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1

PD-L1 的 N 端 IgV 样结构域 (D1) 和完整胞外区 (D1D2) 的序列特异性 (1)H、(13)C 和 (15)N 骨架 NMR 归属

期刊:Biomolecular Nmr Assignments
影响因子:0.6
doi:10.1007/s12104-022-10092-5
Walker, Kayleigh; Waters, Lorna C; Kelly, Geoff; Muskett, Frederick W; Carr, Mark D
PD-L1
发表日期：2022
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Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA

人类 Pol κ 与 DNA 和单泛素化 PCNA 结合的低温电子显微镜结构

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-26251-6
Claudia Lancey #, Muhammad Tehseen #, Souvika Bakshi, Matthew Percival, Masateru Takahashi, Mohamed A Sobhy, Vlad S Raducanu, Kerry Blair, Frederick W Muskett, Timothy J Ragan, Ramon Crehuet, Samir M Hamdan, Alfredo De Biasio
表观遗传
发表日期：2021
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A glycopyrronium bromide 1% cream for topical treatment of primary axillary hyperhidrosis: efficacy and safety results from a phase IIIa randomized controlled trial

用于局部治疗原发性腋窝多汗症的1%格隆溴铵乳膏：一项IIIa期随机对照试验的疗效和安全性结果

期刊:British Journal of Dermatology
影响因子:9.6
doi:10.1111/bjd.19810
Abels, C; Soeberdt, M; Kilic, A; Reich, H; Knie, U; Jourdan, C; Schramm, K; Heimstaedt-Muskett, S; Masur, C; Szeimies, R-M
发表日期：2021
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