日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of the SARS-CoV-2 Papain-Like Protease Inhibitor MR1-114: From Structure-Based Design to In Vivo Antiviral Efficacy

SARS-CoV-2木瓜蛋白酶样蛋白酶抑制剂MR1-114的发现:从基于结构的药物设计到体内抗病毒功效

Gannarapu, Malla Reddy; Indukuri, Divakar; Holberg, Cameron; Ratia, Kiira; Ramos, Omar Lozano; Cardoza, Savio; Velma, Ganga Reddy; Musku, Soumya Reddy; Qi, Zuohuang; Slilaty, Steve; Li, Zuomei; Rong, Lijun; Thatcher, Gregory R J; Xiong, Rui

Evaluation of Bridge Capture technology for mutation profiling in liquid biopsies of metastatic colorectal cancer patients

评估桥接捕获技术在转移性结直肠癌患者液体活检突变谱分析中的应用

Ganesan, Aparna; Korkiakoski, Anttoni; Adamusová, Simona; Musku, Anna; Rantasalo, Tuula; Laine, Nea; Andersson, Emma; Osterlund, Emerik; Ovissi, Ali; Halonen, Päivi; Hirvonen, Tatu; Kim, Jorma; Laine, Jukka; Silvoniemi, Antti; Minn, Heikki; Blomster, Juuso; Anttonen, Anna-Kaisa; Kytölä, Soili; Osterlund, Pia; Pursiheimo, Juha-Pekka; Nummela, Pirjo; Tamminen, Manu; Ristimäki, Ari

In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands

寻找非脂肪生成性ABCA1诱导剂(NLAI):精准共调节器TR-FRET识别LXR配体的多种特征

Laham, Megan S; Ackerman-Berrier, Martha; Alam, Fahmida; Turner, Sarah; Velma, Ganga Reddy; Penton, Christopher; Musku, Soumya Reddy; Rana, Manan; Kumar, Senthil; Annadurai, Anandhan; Sulaiman, Maha Ibrahim; Ma, Nina; Thatcher, Gregory R J

Vulvar dermatoses: A cross-sectional study of etiology, dermoscopic findings, and impact on the quality of life

外阴皮肤病:病因、皮肤镜检查结果及其对生活质量影响的横断面研究

Karishni, Chittarvu; Musku, Tejaswaroop; Saisharanya, Bommakanti; Reddy, G Shambhavi; Chintagunta, Sudha Rani

Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity

SARS-CoV-2 木瓜蛋白酶样蛋白酶 (PLpro) 的非共价抑制剂:体外和体内抗病毒活性

Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher

Nonlipogenic ABCA1 Inducers (NLAI) for Alzheimer's Disease Validated in a Mouse Model Expressing Human APOE3/APOE4.

在表达人类 APOE3/APOE4 的小鼠模型中验证了非脂肪生成 ABCA1 诱导剂 (NLAI) 对阿尔茨海默病的疗效

Velma Ganga Reddy, Laham Megan S, Lewandowski Cutler, Valencia-Olvera Ana C, Balu Deebika, Moore Annabelle, Ackerman-Berrier Martha, Rychetsky Pavel, Penton Christopher, Musku Soumya Reddy, Annadurai Anandhan, Sulaiman Maha Ibrahim, Ma Nina, J Thatcher Gregory R

Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress

烟酰胺磷酸核糖转移酶正向变构调节剂可减轻神经元氧化应激

Gordon-Blake, Jesse; Ratia, Kiira; Weidig, Victoria; Velma, Ganga Reddy; Ackerman-Berrier, Martha; Penton, Christopher; Musku, Soumya Reddy; Alves, Erick T M; Driver, Tom; Tai, Leon; Thatcher, Gregory R J

Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs)

烟酰胺磷酸核糖转移酶(NAMPT)正变构调节剂(N-PAMs)的合成、优化及构效关系

Shen, Zhengnan; Ratia, Kiira; Krider, Isabella; Ackerman-Berrier, Martha; Penton, Christopher; Musku, Soumya Reddy; Gordon-Blake, Jesse M; Laham, Megan S; Christie, Nicholas; Ma, Nina; Fu, Jiqiang; Xiong, Rui; Courey, Jenna M; Velma, Ganga Reddy; Thatcher, Gregory R J

Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD()

烟酰胺磷酸核糖转移酶变构调节提升细胞NAD<sup>+</sup>水平的机制

Ratia, Kiira M; Shen, Zhengnan; Gordon-Blake, Jesse; Lee, Hyun; Laham, Megan S; Krider, Isabella S; Christie, Nicholas; Ackerman-Berrier, Martha; Penton, Christopher; Knowles, Natalie G; Musku, Soumya Reddy; Fu, Jiqiang; Velma, Ganga Reddy; Xiong, Rui; Thatcher, Gregory R J