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Recognition-induced destabilization: controlled release from molecularly imprinted chitosan nanoparticles via specific, non-catalytic enzyme recognition

识别诱导的不稳定化：通过特异性非催化酶识别实现分子印迹壳聚糖纳米粒子的可控释放

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d5ra05081b

Taha, Mutasem O; Dmour, Isra; Saeed, Ramzi Mukred; Alfararjeh, Taqwa; Jum'h, Inshad; Dahabiyeh, Lina A

发表日期：2025

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Quinoline and coumarin isoxazole derivatives: synthesis, antitumor evaluation and molecular docking studies with Bcl-2

喹啉和香豆素异噁唑衍生物：合成、抗肿瘤活性评价及与Bcl-2的分子对接研究

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d5ra05483d

Piškor, Martina; Ter, Marina; Persoons, Leentje; Daelemans, Dirk; Adel, Ahmed; Taha, Mutasem O; Milić, Astrid; Sedić, Mirela; Raić-Malić, Silvana

Reported Adverse Effects and Attitudes among Arab Populations Following COVID-19 Vaccination: A Large-Scale Multinational Study Implementing Machine Learning Tools in Predicting Post-Vaccination Adverse Effects Based on Predisposing Factors

阿拉伯人群接种新冠疫苗后报告的不良反应和态度：一项大规模多国研究，应用机器学习工具基于易感因素预测疫苗接种后的不良反应

期刊:Vaccines

影响因子:3.4

doi:10.3390/vaccines10030366

Hatmal, Ma'mon M; Al-Hatamleh, Mohammad A I; Olaimat, Amin N; Mohamud, Rohimah; Fawaz, Mirna; Kateeb, Elham T; Alkhairy, Omar K; Tayyem, Reema; Lounis, Mohamed; Al-Raeei, Marwan; Dana, Rasheed K; Al-Ameer, Hamzeh J; Taha, Mutasem O; Bindayna, Khalid M

Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease

通过与青霉素共价修饰抑制淀粉样蛋白-β的聚集；与阿尔茨海默病有潜在相关性

期刊:Biochemistry and Biophysics Reports

影响因子:2.3

doi:10.1016/j.bbrep.2021.100943

Izzeddin Alsalahat, Zubida M Al-Majdoub, Mutasem O Taha, Jill Barber, Harmesh Aojula, Nigel Hodson, Sally Freeman

表观遗传

发表日期：2021

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Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2

对SARS-CoV-2、SARS-CoV和MERS-CoV刺突蛋白的结构和分子进行全面比较，并探讨它们与ACE2的相互作用

期刊:Cells

影响因子:5.2

doi:10.3390/cells9122638

Hatmal, Ma'mon M; Alshaer, Walhan; Al-Hatamleh, Mohammad A I; Hatmal, Malik; Smadi, Othman; Taha, Mutasem O; Oweida, Ayman J; Boer, Jennifer C; Mohamud, Rohimah; Plebanski, Magdalena

Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA)

通过基于对接的比较分子间接触分析 (dbCICA) 对新型 Aurora-A 激酶抑制剂进行基于结构的发现和生物活性评估作为抗癌剂

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules25246003

Majd S Hijjawi, Reem Fawaz Abutayeh, Mutasem O Taha

肿瘤

发表日期：2020

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Degradability of chitosan micro/nanoparticles for pulmonary drug delivery

壳聚糖微/纳米颗粒的降解性及其在肺部给药中的应用

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2019.e01684

Islam, Nazrul; Dmour, Isra; Taha, Mutasem O

发表日期：2019

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Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory syndrome (MERS) coronavirus

蝙蝠 HKU4 冠状病毒 3CLpro 抑制剂的计算建模，作为开发针对新兴中东呼吸综合征 (MERS) 冠状病毒的抗病毒药物的工具

期刊:Journal of Molecular Recognition

影响因子:2.3

doi:10.1002/jmr.2644

Areej Abuhammad, Rua'a A Al-Aqtash, Brandon J Anson, Andrew D Mesecar, Mutasem O Taha

The anticancer activity of the substituted pyridone-annelated isoindigo (5'-Cl) involves G0/G1 cell cycle arrest and inactivation of CDKs in the promyelocytic leukemia cell line HL-60

取代吡啶酮缩异靛蓝 (5'-Cl) 的抗癌活性涉及早幼粒细胞白血病细胞系 HL-60 中的 G0/G1 细胞周期停滞和 CDK 失活

期刊:Cellular Physiology and Biochemistry

影响因子:2.5

doi:10.1159/000374003

Ayman M Saleh, Ahmad Aljada, Mustafa M El-Abadelah, Mutasem O Taha, Salim S Sabri, Jalal A Zahra, Mohammad Azhar Aziz

Synthesis, and evaluation of novel low nanomolar isoindigo-based RET kinase inhibitors

新型低纳摩尔级异靛蓝基RET激酶抑制剂的合成与评价

Recognition-induced destabilization: controlled release from molecularly imprinted chitosan nanoparticles via specific, non-catalytic enzyme recognition

识别诱导的不稳定化：通过特异性非催化酶识别实现分子印迹壳聚糖纳米粒子的可控释放

Quinoline and coumarin isoxazole derivatives: synthesis, antitumor evaluation and molecular docking studies with Bcl-2

喹啉和香豆素异噁唑衍生物：合成、抗肿瘤活性评价及与Bcl-2的分子对接研究

Reported Adverse Effects and Attitudes among Arab Populations Following COVID-19 Vaccination: A Large-Scale Multinational Study Implementing Machine Learning Tools in Predicting Post-Vaccination Adverse Effects Based on Predisposing Factors

阿拉伯人群接种新冠疫苗后报告的不良反应和态度：一项大规模多国研究，应用机器学习工具基于易感因素预测疫苗接种后的不良反应

Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease

通过与青霉素共价修饰抑制淀粉样蛋白-β的聚集；与阿尔茨海默病有潜在相关性

Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2

对SARS-CoV-2、SARS-CoV和MERS-CoV刺突蛋白的结构和分子进行全面比较，并探讨它们与ACE2的相互作用

Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA)

通过基于对接的比较分子间接触分析 (dbCICA) 对新型 Aurora-A 激酶抑制剂进行基于结构的发现和生物活性评估作为抗癌剂

Degradability of chitosan micro/nanoparticles for pulmonary drug delivery

壳聚糖微/纳米颗粒的降解性及其在肺部给药中的应用

Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory syndrome (MERS) coronavirus

蝙蝠 HKU4 冠状病毒 3CLpro 抑制剂的计算建模，作为开发针对新兴中东呼吸综合征 (MERS) 冠状病毒的抗病毒药物的工具

The anticancer activity of the substituted pyridone-annelated isoindigo (5'-Cl) involves G0/G1 cell cycle arrest and inactivation of CDKs in the promyelocytic leukemia cell line HL-60

取代吡啶酮缩异靛蓝 (5'-Cl) 的抗癌活性涉及早幼粒细胞白血病细胞系 HL-60 中的 G0/G1 细胞周期停滞和 CDK 失活