日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HJP 272, an endothelin receptor antagonist, and its role in cancer cell migration and invasion

内皮素受体拮抗剂HJP 272及其在癌细胞迁移和侵袭中的作用

Baig, Nabeela; Chilamakuri, Rameswari; Agarwal, Saurabh; Muth, Aaron; Reznik, Sandra E

Gankyrin-Protein Interactions in GI Cancers: A Novel Target of New Therapeutics

胃肠道癌症中的 Gankyrin-蛋白质相互作用:新型治疗靶点

Li, Shuang; Lam, Yuky; Muth, Aaron; Chen, Zhe-Sheng; Wang, Shanzhi

Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders

2,5-取代嘧啶类化合物的合成与评价及其作为小分子gankyrin结合剂的性能

Kanabar, Dipti; Kane, Emma I; Chavan, Tejashri; Laflamme, Taylor M; Suarez, Ethan; Goyal, Mimansa; Gupta, Vivek; Spratt, Donald E; Muth, Aaron

Structural modification of the propyl linker of cjoc42 in combination with sulfonate ester and triazole replacements for enhanced gankyrin binding and anti-proliferative activity

通过对cjoc42的丙基连接基进行结构修饰,并结合磺酸酯和三唑取代,可增强其与gankyrin的结合能力和抗增殖活性。

Chavan, Tejashri; Kanabar, Dipti; Patel, Kinjal; Laflamme, Taylor M; Riyazi, Maryam; Spratt, Donald E; Muth, Aaron

Second Generation Small Molecule Inhibitors of Gankyrin for the Treatment of Pediatric Liver Cancer

第二代小分子Gankyrin抑制剂用于治疗儿童肝癌

D'Souza, Amber M; Gnanamony, Manu; Thomas, Maria; Hanley, Peter; Kanabar, Dipti; de Alarcon, Pedro; Muth, Aaron; Timchenko, Nikolai

Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.

将抗癫痫药物用于治疗胶质母细胞瘤

Yadav Anjali, Alnakhli Ali, Vemana Hari Priya, Bhutkar Shraddha, Muth Aaron, Dukhande Vikas V

Bioinspired particle engineering for non-invasive inhaled drug delivery to the lungs

仿生粒子工程技术用于非侵入性吸入式肺部药物输送

Shukla, Snehal K; Sarode, Apoorva; Kanabar, Dipti D; Muth, Aaron; Kunda, Nitesh K; Mitragotri, Samir; Gupta, Vivek

Bypassing P-glycoprotein mediated efflux of afatinib by cyclodextrin complexation - Evaluation of intestinal absorption and anti-cancer activity

通过环糊精络合绕过P-糖蛋白介导的阿法替尼外排——肠道吸收及抗癌活性评价

Parvathaneni, Vineela; Elbatanony, Rasha S; Shukla, Snehal K; Kulkarni, Nishant S; Kanabar, Dipti D; Chauhan, Gautam; Ayehunie, Seyoum; Chen, Zhe-Sheng; Muth, Aaron; Gupta, Vivek

Repurposing Bedaquiline for Effective Non-Small Cell Lung Cancer (NSCLC) Therapy as Inhalable Cyclodextrin-Based Molecular Inclusion Complexes

将贝达喹啉重新用于有效的非小细胞肺癌(NSCLC)治疗,开发为可吸入的环糊精基分子包合物

Parvathaneni, Vineela; Elbatanony, Rasha S; Goyal, Mimansa; Chavan, Tejashri; Vega, Nathan; Kolluru, Srikanth; Muth, Aaron; Gupta, Vivek; Kunda, Nitesh K

Development of pharmaceutically scalable inhaled anti-cancer nanotherapy - Repurposing amodiaquine for non-small cell lung cancer (NSCLC).

开发可大规模生产的吸入式抗癌纳米疗法——将阿莫地喹用于治疗非小细胞肺癌(NSCLC)

Parvathaneni Vineela, Kulkarni Nishant S, Chauhan Gautam, Shukla Snehal K, Elbatanony Rasha, Patel BrijeshKumar, Kunda Nitesh K, Muth Aaron, Gupta Vivek