日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Phase III Randomized Trial of Integrated Genomics and Avatar Models for Personalized Treatment of Pancreatic Cancer: The AVATAR Trial

一项整合基因组学和虚拟化身模型用于胰腺癌个性化治疗的III期随机试验：AVATAR试验

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-23-4026
Sarno, Francesca; Tenorio, Jair; Perea, Sofia; Medina, Laura; Pazo-Cid, Roberto; Juez, Ignacio; Garcia-Carbonero, Rocío; Feliu, Jaime; Guillen-Ponce, Carmen; Lopez-Casas, Pedro P; Guerra, Carmen; Duran, Yolanda; López-Acosta, José Francisco; Alonso, Carolina; Esquivel, Estrella; Dopazo, Ana; Akshinthala, Dipikaa; Muthuswamy, Senthil K; Lapunzina, Pablo; Bockorny, Bruno; Hidalgo, Manuel
胰腺癌
肿瘤
肿瘤免疫
发表日期：2025
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Novel emerging cell and organoid systems for the study of drug metabolism and toxicity in humans

用于研究人类药物代谢和毒性的新型细胞和类器官系统

期刊:Cold Spring Harbor Perspectives in Medicine
影响因子:10.1
doi:10.1101/cshperspect.a041661
Muthuswamy, Senthil K; Brugge, Joan S; Gracey, Emily G; Lampe, Jed N
毒理研究
3D/类器官
代谢
细胞生物学
发表日期：2025
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Head and neck tumor organoid grown under simplified media conditions model tumor biology and chemoradiation responses.

在简化的培养基条件下生长的头颈部肿瘤类器官可以模拟肿瘤生物学和放化疗反应

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-88082-5
Li Weilin, Nishino Michiya, Reed Eric, Akshinthala Dipikaa, Pasha Hamdan Ahmed, Anderson Erik S, Huang Ling, Hebestreit Hannah, Monti Stefano, Gomez Ernest D, Jalisi Scharukh M, Muthuswamy Senthil K
肿瘤
3D/类器官
发表日期：2025
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CD320 expression is increased in breast cancer stem cells but does not promote their expansion or alter key histone methylation marks.

CD320 在乳腺癌干细胞中表达增加，但并不促进其增殖或改变关键的组蛋白甲基化标记。

期刊:microPublication Biology
影响因子:
doi:10.17912/micropub.biology.001696
Carney Christine, Jenkins Lisa, Jewell Connor, Carter Rachel, Mann Puneet, Tang Binwu, Muthuswamy Senthil, Wakefield Lalage
肿瘤
表观遗传
肿瘤免疫
细胞生物学
CD320
乳腺癌
CD3
干细胞
发育与干细胞
发表日期：2025
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A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer

胰腺癌生物标志物发现：循环细胞外囊泡的大规模蛋白质组学资源

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.87369
Bockorny, Bruno; Muthuswamy, Lakshmi; Huang, Ling; Hadisurya, Marco; Maria Lim, Christine; Tsai, Leo L; Gill, Ritu R; Wei, Jesse L; Bullock, Andrea J; Grossman, Joseph E; Besaw, Robert J; Narasimhan, Supraja; Tao, Weiguo Andy; Perea, Sofia; Sawhney, Mandeep S; Freedman, Steven D; Hildago, Manuel; Iliuk, Anton; Muthuswamy, Senthil K
肿瘤
肿瘤免疫
细胞生物学
囊泡
胰腺癌
发表日期：2024
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A Large-Scale Proteomics Resource of Circulating Extracellular Vesicles for Biomarker Discovery in Pancreatic Cancer

胰腺癌生物标志物发现：循环细胞外囊泡的大规模蛋白质组学资源

期刊:
影响因子:
doi:10.1101/2023.03.13.23287216
Bockorny, Bruno; Muthuswamy, Lakshmi; Huang, Ling; Hadisurya, Marco; Lim, Christine Maria; Tsai, Leo L; Gill, Ritu R; Wei, Jesse L; Bullock, Andrea J; Grossman, Joseph E; Besaw, Robert J; Narasimhan, Supraja; Tao, W Andy; Perea, Sofia; Sawhney, Mandeep S; Freedman, Steven D; Hidalgo, Manuel; Iliuk, Anton; Muthuswamy, Senthil K
肿瘤
肿瘤免疫
细胞生物学
囊泡
胰腺癌
发表日期：2024
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Personalized tumor vaccine for pancreatic cancer

针对胰腺癌的个性化肿瘤疫苗

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-022-03237-x
Orr, Shira; Huang, Ling; Moser, James; Stroopinsky, Dina; Gandarilla, Omar; DeCicco, Cori; Liegel, Jessica; Tacettin, Cansu; Ephraim, Adam; Cheloni, Giulia; Torres, Daniela; Kufe, Donald; Rosenblatt, Jacalyn; Hidalgo, Manuel; Muthuswamy, Senthil K; Avigan, David
胰腺癌
肿瘤
肿瘤免疫
发表日期：2023
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Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer.

建立生成和维持雌激素受体阳性乳腺癌类器官模型的条件

期刊:
影响因子:
doi:10.21203/rs.3.rs-3341539/v1
Oliphant Michael Uj, Akshinthala Dipikaa, Muthuswamy Senthil K
肿瘤
乳腺癌
发表日期：2023
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Oncogenic GNAS uses PKA-dependent and independent mechanisms to induce cell proliferation in human pancreatic ductal and acinar organoids.

致癌的 GNAS 利用 PKA 依赖性和非依赖性机制诱导人胰腺导管和腺泡类器官中的细胞增殖

期刊:
影响因子:
doi:10.1101/2023.01.16.524220
Desai Ridhdhi, Muthuswamy Senthil
细胞生物学
Human
3D/类器官
发表日期：2023
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Abnormal exocrine-endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8

异常的外分泌-内分泌细胞间相互作用促进MODY8中β细胞功能障碍和丢失

期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-021-00516-2
Kahraman, Sevim; Dirice, Ercument; Basile, Giorgio; Diegisser, Danielle; Alam, Jahedul; Johansson, Bente B; Gupta, Manoj K; Hu, Jiang; Huang, Ling; Soh, Chew-Li; Huangfu, Danwei; Muthuswamy, Senthil K; Raeder, Helge; Molven, Anders; Kulkarni, Rohit N
细胞生物学
发表日期：2022
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