The nonglycosylated variant in therapeutic monoclonal antibodies preferentially forms large aggregates under typical thermal stresses used in forced degradation studies
治疗性单克隆抗体中的非糖基化变体在强制降解研究中常用的典型热应力下优先形成大的聚集体。
期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2025.2543768
Liu, Gao-Yuan; Kim, Jenny Kim; Tang, Shuli; Yan, Yuetian; Hopkins, Mandi; Laredo, Dalia; Yang, Teng-Chieh; Mutino, James; Kamen, Douglas E; Graham, Kenneth S; Shameem, Mohammed; Wang, Shunhai; Li, Ning
