日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NSUN2 mediates intestinal stem cell expansion and colorectal tumour initiation via MAPK/ERK signalling

NSUN2通过MAPK/ERK信号通路介导肠道干细胞扩增和结直肠肿瘤起始

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08560-0
Bastem Akan, Aslihan; Billard, Caroline V; Chen, Szu-Ying; Huang, Po-Hsien; Cammareri, Patrizia; Rajasekaran, Vidya; Hall, Adam E; Preyzner, Paula; Pohl, Sebastian Öther-Gee; Farrington, Susan M; Dunlop, Malcolm G; Din, Farhat V N; Myant, Kevin B
肿瘤
发育与干细胞
肿瘤免疫
信号转导
MAPK/ERK
干细胞
细胞生物学
发表日期：2026
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Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.

11q23.1 的基因变异通过结肠簇状细胞转录激活因子 POU2AF2 的失调而增加结直肠癌的风险

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2024-332121
Rajasekaran Vidya, Harris Bradley T, Osborn Ruby T, Smillie Claire, Donnelly Kevin, Bacou Marion, Esiri-Bloom Edward, Ooi Li-Yin, Allan Morven, Walker Marion, Reid Stuart, Meynert Alison, Grimes Graeme, Blackmur James P, Vaughan-Shaw Peter G, Law Philip J, Fernández-Rozadilla Ceres, Tomlinson Ian, Houlston Richard S, Myant Kevin B, Din Farhat Vn, Timofeeva Maria, Dunlop Malcolm G, Farrington Susan M
细胞生物学
肿瘤免疫
发表日期：2025
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Be like water, my cells: cell plasticity and the art of transformation

像水一样，我的细胞：细胞可塑性和转化的艺术

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2023.1272730
Cammareri, Patrizia; Myant, Kevin B
细胞生物学
发表日期：2023
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Design, Synthesis, and Biological Evaluation of SSE1806, a Microtubule Destabilizer That Overcomes Multidrug Resistance

SSE1806 的设计、合成及生物学评价：一种克服多药耐药性的微管去稳定剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00258
Firdous, Farhat; Riaz, Sharon; Furqan, Muhammad; Fozail, Salman; Fatima, Khushboo; Pohl, Sebastian Öther-Gee; Doleschall, Nora Julia; Myant, Kevin B; Kahfi, Jordan; Emwas, Abdul-Hamid; Jaremko, Mariusz; Chotana, Ghayoor Abbas; Saleem, Rahman Shah Zaib; Faisal, Amir
发表日期：2023
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HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

HUWE1 是一种重要的结肠肿瘤抑制基因，它能阻止 MYC 信号传导、DNA 损伤积累和肿瘤发生。

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.201606684
Myant, Kevin B; Cammareri, Patrizia; Hodder, Michael C; Wills, Jimi; Von Kriegsheim, Alex; Győrffy, Balázs; Rashid, Mamun; Polo, Simona; Maspero, Elena; Vaughan, Lynsey; Gurung, Basanta; Barry, Evan; Malliri, Angeliki; Camargo, Fernando; Adams, David J; Iavarone, Antonio; Lasorella, Anna; Sansom, Owen J
MYC
信号转导
肿瘤
肿瘤免疫
发表日期：2017
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ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

RAC1触发的ROS产生和NF-κB激活促进WNT驱动的肠道干细胞增殖和结直肠癌的发生。

期刊:Cell Stem Cell
影响因子:20.4
doi:10.1016/j.stem.2013.04.006
Myant, Kevin B; Cammareri, Patrizia; McGhee, Ewan J; Ridgway, Rachel A; Huels, David J; Cordero, Julia B; Schwitalla, Sarah; Kalna, Gabriela; Ogg, Erinn-Lee; Athineos, Dimitris; Timpson, Paul; Vidal, Marcos; Murray, Graeme I; Greten, Florian R; Anderson, Kurt I; Sansom, Owen J
肿瘤
肠癌
RAC1
肿瘤免疫
细胞生物学
NF-κB
干细胞
发育与干细胞
发表日期：2013
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Rac1 drives intestinal stem cell proliferation and regeneration

Rac1驱动肠道干细胞增殖和再生

期刊:Cell Cycle
影响因子:3.4
doi:10.4161/cc.26031
Myant, Kevin B; Scopelliti, Alessandro; Haque, Sara; Vidal, Marcos; Sansom, Owen J; Cordero, Julia B
细胞生物学
发育与干细胞
干细胞
发表日期：2013
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Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.

Apc 缺失后，细胞周期蛋白 D2-细胞周期蛋白依赖性激酶 4/6 是有效增殖和肿瘤发生所必需的

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-10-0315
Cole Alicia M, Myant Kevin, Reed Karen R, Ridgway Rachel A, Athineos Dimitris, Van den Brink Gijs R, Muncan Vanesa, Clevers Hans, Clarke Alan R, Sicinski Peter, Sansom Owen J
细胞生物学
肿瘤
肿瘤免疫
发表日期：2010
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Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

黏着斑激酶是 Wnt/c-Myc 信号下游肠道再生和肿瘤发生所必需的

期刊:Developmental Cell
影响因子:8.7
doi:10.1016/j.devcel.2010.07.015
Ashton Gabrielle H, Morton Jennifer P, Myant Kevin, Phesse Toby J, Ridgway Rachel A, Marsh Victoria, Wilkins Julie A, Athineos Dimitris, Muncan Vanesa, Kemp Richard, Neufeld Kristi, Clevers Hans, Brunton Valerie, Winton Douglas J, Wang Xiaoyan, Sears Rosalie C, Clarke Alan R, Frame Margaret C, Sansom Owen J
肿瘤
发表日期：2010
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Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression

Tiam1-Rac信号通路在双极纺锤体组装过程中拮抗Eg5的作用，从而促进染色体排列。

期刊:Current Biology
影响因子:7.5
doi:10.1016/j.cub.2010.02.033
Woodcock, Simon A; Rushton, Helen J; Castañeda-Saucedo, Eduardo; Myant, Kevin; White, Gavin R M; Blyth, Karen; Sansom, Owen J; Malliri, Angeliki
信号转导
发表日期：2010
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