日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in mice.

神经元 SEL1L-HRD1 内质网相关降解对于小鼠的运动功能和生存至关重要。

Torres Mauricio, Lu You, Pederson Brent, Wang Hui, Gretzinger Anna, Lin Liangguang L, Hwang Jiwon, Chen Xinxin, Rupp Alan C, Tomlinson Abigail J, Scott Andrew J, Zhao Zhen, Wahl Daniel R, Myers Martin G Jr, Lyssiotis Costas A, Qi Ling

A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity

下丘脑中一种独特的、对瘦素敏感的神经元群限制了饮食诱导肥胖中的过度摄食和体重增加。

Belmont-Rausch, Dylan M; Kapel, Benedicte Schultz; Tomlinson, Abigail J; Ding, Chao; Duensing, Allison M; Coester, Bernd; Mathiesen, Cecilie Vad; Cabot, Leonie; Brown, Jenny M; Kruse, Charlotte Høy; Clemmensen, Christoffer; Schwartz, Michael W; Fenselau, Henning; Myers, Martin G Jr; Pers, Tune H

Molecularly defined subpopulations of leptin receptor neurons dissociate the control of food intake from blood pressure

瘦素受体神经元的分子亚群将食物摄入的控制与血压控制分离。

Duensing, Allison M; Belmont-Rausch, Dylan; Tomlinson, Abigail J; Crowley, Aiden; Sass, Frederike; Heaton, Elizabeth; Coester, Bernd; Brown, Jenny M; Hassan, Shad; Wu, Zhe; Qi, Nathan; Olson, David P; Sabatini, Paul V; Myers, Martin G Jr; Pers, Tune H

Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist

共表达 Glp1r-Lepr 的神经元通过 GLP-1/瘦素双重激动剂调节食物摄入和体重的抑制。

Polex-Wolf, Joseph; Deibler, Kristine; Hogendorf, Wouter Frederik Johan; Bau, Sarah; Glendorf, Tine; Stidsen, Carsten Enggaard; Tornøe, Christian Wenzel; Tiantang, Dong; Lundh, Sofia; Pyke, Charles; Tomlinson, Abigail J; Kernodle, Stace; Magrisso, Irwin Jack; Conde-Frieboes, Kilian W; Myers, Martin G Jr; Knudsen, Lotte Bjerre; Seeley, Randy J

Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice.

瘦素受体细胞的谷氨酸神经传递是雌性小鼠正常青春期发育和生殖功能所必需的

de Miera Cristina Sáenz, Bellefontaine Nicole, Allen Susan J, Myers Martin G Jr, Elias Carol F

LepRb+ cell-specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice

LepRb+细胞特异性敲除Slug基因可减轻小鼠的肥胖和非酒精性脂肪肝疾病。

Kim, Min-Hyun; Li, Yuan; Zheng, Qiantao; Jiang, Lin; Myers, Martin G Jr; Wu, Wen-Shu; Rui, Liangyou

Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease

表达瘦素受体的神经元Sh2b1支持交感神经系统,并能预防肥胖和代谢性疾病。

Jiang, Lin; Su, Haoran; Wu, Xiaoyin; Shen, Hong; Kim, Min-Hyun; Li, Yuan; Myers, Martin G Jr; Owyang, Chung; Rui, Liangyou

Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism

鉴定对STAT3非依赖性代谢调控至关重要的瘦素受体序列

Barnes, Tammy M; Shah, Kimi; Allison, Margaret B; Steinl, Gabrielle K; Gordian, Desiree; Sabatini, Paul V; Tomlinson, Abigail J; Cheng, Wenwen; Jones, Justin C; Zhu, Qing; Faber, Chelsea; Myers, Martin G Jr

Hypothalamic and Cell-Specific Transcriptomes Unravel a Dynamic Neuropil Remodeling in Leptin-Induced and Typical Pubertal Transition in Female Mice

下丘脑和细胞特异性转录组揭示了瘦素诱导和典型青春期雌性小鼠过渡过程中神经毡的动态重塑

Han, Xingfa; Burger, Laura L; Garcia-Galiano, David; Sim, Seokmin; Allen, Susan J; Olson, David P; Myers, Martin G Jr; Elias, Carol F

Transcriptional and physiological roles for STAT proteins in leptin action

STAT蛋白在瘦素作用中的转录和生理功能

Pan, Warren; Allison, Margaret B; Sabatini, Paul; Rupp, Alan; Adams, Jessica; Patterson, Christa; Jones, Justin C; Olson, David P; Myers, Martin G Jr