日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

LZAP 的缺失使 p53 失活,并以 p53 依赖的方式调节细胞对 DNA 损伤的敏感性

J J Wamsley, C Gary, A Biktasova, M Hajek, G Bellinger, R Virk, N Issaeva, W G Yarbrough

Copper and Chemotherapy Drug Accumulate when the Ctr1 Transporter Is Not Processed by Cathepsin Proteases(♦): Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain

当 Ctr1 转运蛋白未被组织蛋白酶加工时,铜和化疗药物会积累(♦):组织蛋白酶通过切割 Ctr1 金属结合胞外结构域来控制铜和顺铂的积累。

Bykov, Vladimir J N; Issaeva, Natalia; Zache, Nicole; Shilov, Alexandre; Hultcrantz, Monica; Bergman, Jan; Selivanova, Galina; Wiman, Klas G

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

ROS 依赖的 JNK 激活将 p53 转化为致癌基因的有效抑制剂,从而导致细胞凋亡

Y Shi, F Nikulenkov, J Zawacka-Pankau, H Li, R Gabdoulline, J Xu, S Eriksson, E Hedström, N Issaeva, A Kel, E S J Arnér, G Selivanova

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

TrkC 信号在腺样囊性癌中被激活,需要 NT-3 来刺激侵袭行为

S V Ivanov, A Panaccione, B Brown, Y Guo, C A Moskaluk, M J Wick, J L Brown, A V Ivanova, N Issaeva, A K El-Naggar, W G Yarbrough