日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Caregiver-reported Patient Experiences with Duchenne Muscular Dystrophy: Qualitative In-trial Interviews 1 Year After Delandistrogene Moxeparvovec in the Pivotal EMBARK Trial

照护者报告的杜氏肌营养不良症患者体验:关键性 EMBARK 试验中 Delandistrogene Moxeparvovec 治疗 1 年后的定性试验内访谈

Audhya, Ivana; Nacson, Alise B; Gooch, Katherine; Basnyat, Bonita; Slota, Christina; Martin, Susan; Murphy, Alex; Lansdall, Claire J; Ciobanu, Teofil; Nascimento, Andres; Veerapandiyan, Aravindhan

PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

PALB2 和 53BP1 调控切除后同源重组 DNA 修复

Yifan Wang ,Yan Coulombe ,Wei-Ting Yueh ,Gregory D Conway ,Larissa Milano ,David J Glass ,Mélissa Thomas ,Amélie Rodrigue ,Joseph Nacson ,Dongbo Lu ,Andrea J Bernhardy ,Robert G Betsch ,Alyssa I Russo ,Gamal A Elfar ,Kathy Q Cai ,Joseph R Testa ,Mark Andrake ,Roland Dunbrack ,Gaorav P Gupta ,Bing Xia ,Eloise Dray ,Jean-Yves Masson ,Neil Johnson

Development and refinement of the Clinical Global Impression of Improvement for Non-seizure Symptoms measure in Dravet syndrome and Lennox-Gastaut syndrome

Dravet综合征和Lennox-Gastaut综合征非癫痫症状临床总体印象改善量表的开发和完善

Andrews, J Scott; Shah, Drishti; Nacson, Alise; Symonds, Tara; Hughes, Sophie; Asgharnejad, Mahnaz; Benitez, Arturo; Sams, Lara

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Brca1 功能的遗传分离揭示了突变依赖的 Polθ 脆弱性

John J Krais, David J Glass, Ilse Chudoba, Yifan Wang, Wanjuan Feng, Dennis Simpson, Pooja Patel, Zemin Liu, Ryan Neumann-Domer, Robert G Betsch, Andrea J Bernhardy, Alice M Bradbury, Jason Conger, Wei-Ting Yueh, Joseph Nacson, Richard T Pomerantz, Gaorav P Gupta, Joseph R Testa, Neil Johnson

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

TET2 和 DNMT3A 突变对 DNA 修复和白血病细胞对 PARP 抑制剂的敏感性产生不同的影响

Silvia Maifrede ,Bac Viet Le ,Margaret Nieborowska-Skorska ,Konstantin Golovine ,Katherine Sullivan-Reed ,Wangisa M B Dunuwille ,Joseph Nacson ,Michael Hulse ,Kelsey Keith ,Jozef Madzo ,Lisa Beatrice Caruso ,Zachary Gazze ,Zhaorui Lian ,Antonella Padella ,Kumaraswamy N Chitrala ,Boris A Bartholdy ,Ksenia Matlawska-Wasowska ,Daniela Di Marcantonio ,Giorgia Simonetti ,Georg Greiner ,Stephen M Sykes ,Peter Valent ,Elisabeth M Paietta ,Martin S Tallman ,Hugo F Fernandez ,Mark R Litzow ,Mark D Minden ,Jian Huang ,Giovanni Martinelli ,George S Vassiliou ,Italo Tempera ,Katarzyna Piwocka ,Neil Johnson ,Grant A Challen ,Tomasz Skorski

BRCA1 Mutational Complementation Induces Synthetic Viability

BRCA1突变互补诱导合成生存能力

Joseph Nacson ,Daniela Di Marcantonio ,Yifan Wang ,Andrea J Bernhardy ,Emma Clausen ,Xiang Hua ,Kathy Q Cai ,Esteban Martinez ,Wanjuan Feng ,Elsa Callén ,Wei Wu ,Gaorav P Gupta ,Joseph R Testa ,André Nussenzweig ,Stephen M Sykes ,Neil Johnson

BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance

BRCA1 内含子 Alu 元件驱动基因重排和 PARP 抑制剂耐药性

Yifan Wang, Andrea J Bernhardy, Joseph Nacson, John J Krais, Yin-Fei Tan, Emmanuelle Nicolas, Marc R Radke, Elizabeth Handorf, Alba Llop-Guevara, Judith Balmaña, Elizabeth M Swisher, Violeta Serra, Suraj Peri, Neil Johnson

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

BRCA1突变特异性反应对53BP1缺失诱导的同源重组和PARP抑制剂耐药性的影响

Joseph Nacson ,John J Krais ,Andrea J Bernhardy ,Emma Clausen ,Wanjuan Feng ,Yifan Wang ,Emmanuelle Nicolas ,Kathy Q Cai ,Rossella Tricarico ,Xiang Hua ,Daniela DiMarcantonio ,Esteban Martinez ,Dali Zong ,Elizabeth A Handorf ,Alfonso Bellacosa ,Joseph R Testa ,Andre Nussenzweig ,Gaorav P Gupta ,Stephen M Sykes ,Neil Johnson

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

BRCA1-Δ11q 替代剪接异构体绕过种系突变并促进对 PARP 抑制和顺铂的治疗耐药性

Yifan Wang, Andrea J Bernhardy, Cristina Cruz, John J Krais, Joseph Nacson, Emmanuelle Nicolas, Suraj Peri, Hanneke van der Gulden, Ingrid van der Heijden, Shane W O'Brien, Yong Zhang, Maribel I Harrell, Shawn F Johnson, Francisco J Candido Dos Reis, Paul D P Pharoah, Beth Karlan, Charlie Gourley, D