From DNA-Encoded Library Screening to AM-9747: An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo Efficacy.
从 DNA 编码文库筛选到 AM-9747：一种具有强效口服体内疗效的 MTA 协同 PRMT5 抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c03101
Sarvary Ian, Vestergaard Mikkel, Moretti Loris, Andersson Jan, Peiró CadahÃa Jorge, Cowland Sanne, Flagstad Thomas, Franch Thomas, Gouliaev Alex, Husemoen Gitte, Jacso Tomas, Kronborg Titi, Kuropatnicka Aleksandra, Nadali Anna, Madsen Mads, Nielsen So Ren, Pii David, Ryborg So Ren, Soede Camillia, Allen Jennifer R, Bourbeau Matthew, Li Kexue, Liu Qingyian, Lo Mei-Chu, Madoux Franck, Mardirossian Narbe, Moriguchi Jodi, Ngo Rachel, Peng Chi-Chi, Pettus Liping, Tamayo Nuria, Wang Paul, Kapoor Rajiv, Belmontes Brian, Caenepeel Sean, Hughes Paul, Liu Siyuan, Slemmons Katherine K, Yang Yajing, Xie Fang, Ghimire-Rijal Sudipa, Mukund Susmith, Glad Sanne
