日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice.

将 RNAi 表达构建体通过 AAV 脑脊液内递送至非人灵长类动物和小鼠后,引起背根神经节毒性

Hawley Zachary C E, Pardo Ingrid D, Cao Shaolong, Zavodszky Maria I, Casey Fergal, Ferber Kyle, Luo Yi, Hana Sam, Chen Shukkwan K, Doherty Jessica, Costa Raquel, Cullen Patrick, Liu Yuqing, Carlile Thomas M, Chowdhury Twinkle, Doyle Benjamin, Clarner Pete, Mangaudis Kevin, Guilmette Edward, Bourque Shawn, Koske David, Nadella Murali V P, Trapa Patrick, Hawes Michael L, Raitcheva Denitza, Lo Shih-Ching

STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial

STAT3 反义寡核苷酸 AZD9150 在部分接受过大量预处理的淋巴瘤患者中的疗效:一项 1b 期试验的结果

Reilley, Matthew J; McCoon, Patricia; Cook, Carl; Lyne, Paul; Kurzrock, Razelle; Kim, Youngsoo; Woessner, Richard; Younes, Anas; Nemunaitis, John; Fowler, Nathan; Curran, Michael; Liu, Qinying; Zhou, Tianyuan; Schmidt, Joanna; Jo, Minji; Lee, Samantha J; Yamashita, Mason; Hughes, Steven G; Fayad, Luis; Piha-Paul, Sarina; Nadella, Murali V P; Xiao, Xiaokun; Hsu, Jeff; Revenko, Alexey; Monia, Brett P; MacLeod, A Robert; Hong, David S

AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer

AZD9150 是一种新一代 STAT3 反义寡核苷酸抑制剂,早期证据表明其在淋巴瘤和肺癌治疗中具有临床活性。

Hong, David; Kurzrock, Razelle; Kim, Youngsoo; Woessner, Richard; Younes, Anas; Nemunaitis, John; Fowler, Nathan; Zhou, Tianyuan; Schmidt, Joanna; Jo, Minji; Lee, Samantha J; Yamashita, Mason; Hughes, Steven G; Fayad, Luis; Piha-Paul, Sarina; Nadella, Murali V P; Mohseni, Morvarid; Lawson, Deborah; Reimer, Corinne; Blakey, David C; Xiao, Xiaokun; Hsu, Jeff; Revenko, Alexey; Monia, Brett P; MacLeod, A Robert

AU-rich elements in the 3'-UTR regulate the stability of the 141 amino acid isoform of parathyroid hormone-related protein mRNA

3'-UTR中富含AU的元件调控甲状旁腺激素相关蛋白mRNA的141个氨基酸异构体的稳定性

Luchin, Alexander I; Nadella, Murali V P; Thudi, Nanda K; Dirksen, Wessel P; Gulati, Parul; Fernandez, Soledad A; Rosol, Thomas J

Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation

HTLV-1诱导人外周血单核细胞永生化过程中甲状旁腺激素相关蛋白的表达:对转化过程的意义

Nadella, Murali V P; Shu, Sherry T; Dirksen, Wessel P; Thudi, Nanda K; Nadella, Kiran S; Fernandez, Soledad A; Lairmore, Michael D; Green, Patrick L; Rosol, Thomas J