日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic Investigation of Adociaquinone and Xestoquinone Derivatives in Breast Cancer Cells

阿多西醌和异喹啉衍生物在乳腺癌细胞中的作用机制研究

Zhou, Yu-Dong; Mahdi, Fakhri; Nagle, Nicholas M; Jekabsons, Mika B; Nagle, Dale G

Emerging protein degradation strategies: expanding the scope to extracellular and membrane proteins

新兴的蛋白质降解策略:将范围扩展到细胞外蛋白和膜蛋白

Lin, Jiayi; Jin, Jinmei; Shen, Yiwen; Zhang, Lijun; Gong, Gang; Bian, Huiting; Chen, Hongzhuan; Nagle, Dale G; Wu, Ye; Zhang, Weidong; Luan, Xin

Cytotoxic and antitumor peptides as novel chemotherapeutics

细胞毒性肽和抗肿瘤肽作为新型化疗药物

Luan, Xin; Wu, Ye; Shen, Yi-Wen; Zhang, Hong; Zhou, Yu-Dong; Chen, Hong-Zhuan; Nagle, Dale G; Zhang, Wei-Dong

Biochemical and Anti-Triple Negative Metastatic Breast Tumor Cell Properties of Psammaplins

Psammaplins 的生化特性和抗三阴性转移性乳腺肿瘤细胞特性

Zhou, Yu-Dong; Li, Jun; Du, Lin; Mahdi, Fakhri; Le, Thuy P; Chen, Wei-Lun; Swanson, Steven M; Watabe, Kounosuke; Nagle, Dale G

Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells

卡尔基毒素抑制血管生成,破坏细胞缺氧信号传导,并阻断肿瘤细胞中的线粒体电子传递。

Morgan, J Brian; Liu, Yang; Coothankandaswamy, Veena; Mahdi, Fakhri; Jekabsons, Mika B; Gerwick, William H; Valeriote, Frederick A; Zhou, Yu-Dong; Nagle, Dale G

Toxins in botanical dietary supplements: blue cohosh components disrupt cellular respiration and mitochondrial membrane potential

植物膳食补充剂中的毒素:蓝升麻成分会破坏细胞呼吸和线粒体膜电位

Datta, Sandipan; Mahdi, Fakhri; Ali, Zulfiqar; Jekabsons, Mika B; Khan, Ikhlas A; Nagle, Dale G; Zhou, Yu-Dong

Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis

海洋海绵 Hyrtios communis 中倍半萜的结构及其潜在的抗肿瘤活性

Li, Jun; Du, Lin; Kelly, Michelle; Zhou, Yu-Dong; Nagle, Dale G

Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1

缺氧反应诱导剂:海洋倍半萜醌激活HIF-1

Du, Lin; Zhou, Yu-Dong; Nagle, Dale G

Mechanism-based Screening for Cancer Therapeutics with Examples from the Discovery of Marine Natural Product-based HIF-1 Inhibitors

基于机制的癌症治疗药物筛选——以海洋天然产物来源的HIF-1抑制剂的发现为例

Soejarto, D D; Gyllenhaal, C; Kadushin, M R; Southavong, B; Sydara, K; Bouamanivong, S; Xaiveu, M; Zhang, H-J; Franzblau, S G; Tan, Ghee T; Pezzuto, J M; Riley, M C; Elkington, B G; Waller, D P; Nagle, Dale G; Zhou, Yu-Dong

Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells

抗肿瘤药物的结构和机制:异喹啉类化合物可解偶联细胞呼吸并破坏人乳腺肿瘤细胞中的HIF信号通路

Du, Lin; Mahdi, Fakhri; Datta, Sandipan; Jekabsons, Mika B; Zhou, Yu-Dong; Nagle, Dale G