Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs
癌症中等位基因特异性DNA甲基化增加，其在正常细胞和肿瘤细胞中的密集分布提高了疾病相关调控性SNP的检出率。
期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-020-02059-3
Do, Catherine; Dumont, Emmanuel L P; Salas, Martha; Castano, Angelica; Mujahed, Huthayfa; Maldonado, Leonel; Singh, Arunjot; DaSilva-Arnold, Sonia C; Bhagat, Govind; Lehman, Soren; Christiano, Angela M; Madhavan, Subha; Nagy, Peter L; Green, Peter H R; Feinman, Rena; Trimble, Cornelia; Illsley, Nicholas P; Marder, Karen; Honig, Lawrence; Monk, Catherine; Goy, Andre; Chow, Kar; Goldlust, Samuel; Kaptain, George; Siegel, David; Tycko, Benjamin
肿瘤
表观遗传
肿瘤免疫
DNA甲基化
信号转导
细胞生物学
肿瘤细胞
