日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Path2Omics Enhances Transcriptomic and Methylation Prediction Accuracy from Tumor Histopathology

Path2Omics 提高了基于肿瘤组织病理学的转录组和甲基化预测准确性

Hoang, Danh-Tai; Shulman, Eldad D; Dhruba, Saugato Rahman; Nair, Nishanth Ulhas; Barman, Ranjan Kumar; Cantore, Thomas; Biswas, Sumona; Lalchungnunga, H; Singh, Omkar; Chung, Youngmin; Lee, Joo Sang; Nasrallah, MacLean P; Stone, Eric A; Aldape, Kenneth; Ruppin, Eytan

Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition

代谢依赖性图谱分析表明,过氧化物酶1是ATM抑制剂耐药性的驱动因素。

Li, Haojian; Furusawa, Takashi; Cavero, Renzo; Xiao, Yunjie; Chari, Raj; Wu, Xiaolin; Sun, David; Hartmann, Oliver; Dhall, Anjali; Holewinski, Ronald; Andresson, Thorkell; Karim, Baktiar; Villamor-Payà, Marina; Gallardo, Devorah; Day, Chi-Ping; Pal, Lipika R; Nair, Nishanth Ulhas; Ruppin, Eytan; Aladjem, Mirit I; Pommier, Yves; Diefenbacher, Markus E; Lim, Jung Mi; Levine, Rodney L; Stracker, Travis H; Weyemi, Urbain

Low-GPX4 drives a sustained drug-tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation.

低 GPX4 通过可靶向的适应性 FSP1 上调驱动 TNBC 中持续的耐药性持续状态

Chaudhary Nazia, Mandal Dibita, Choudhary Bhagya Shree, Patra Sushmita, Jain Darshan, Poonia Pritam, Shaikh Shagufa, Tekalkar Siddhi, Malvankar Shivani, Shivashankar Anusha, Jog Eeshrita, Pilankar Leena, Thorat Rahul, Kailje Vaishali V, Khanna Sonal, Manna Subhakankha, Khan Bushra K, Jadhav Anjana, Sharma Kedar, Ramu Soundharya, Sahoo Sarthak, Jolly Mohit Kumar, Dalal Sorab N, Sinha Sanju, Nair Nishanth Ulhas, Ruppin Eytan, Lamballe Fabienne, Maina Flavio, Verma Nandini

Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse.

癌细胞再上皮化增加自噬和DNA损伤:对乳腺癌休眠和复发的影响

Drago-Garcia Diana, Giri Suvendu, Chatterjee Rishita, Simoni-Nieves Arturo, Abedrabbo Maha, Genna Alessandro, Rios Mary Luz Uribe, Lindzen Moshit, Sekar Arunachalam, Gupta Nitin, Aharoni Noa, Bhandari Tithi, Mayalagu Agalyan, Schwarzmüller Luisa, Tarade Nooraldeen, Zhu Rong, Mohan-Raju Harsha-Raj, Karatekin Feride, Roncato Francesco, Eyal-Lubling Yaniv, Keidar Tal, Nof Yam, Belugali Nataraj Nishanth, Bernshtein Karin Shira, Wagner Bettina, Nair Nishanth Ulhas, Sanghvi Neel, Alon Ronen, Seger Rony, Pikarsky Eli, Donzelli Sara, Blandino Giovanni, Wiemann Stefan, Lev Sima, Prywes Ron, Barkan Dalit, Rueda Oscar M, Caldas Carlos, Ruppin Eytan, Shiloh Yosef, Dahlhoff Maik, Yarden Yosef

Path2Omics: Enhanced transcriptomic and methylation prediction accuracy from tumor histopathology

Path2Omics:基于肿瘤组织病理学的转录组和甲基化预测准确性增强

Hoang, Danh-Tai; Shulman, Eldad D; Dhruba, Saugato Rahman; Nair, Nishanth Ulhas; Barman, Ranjan K; Lalchungnunga, H; Singh, Omkar; Nasrallah, MacLean P; Stone, Eric A; Aldape, Kenneth; Ruppin, Eytan

Chromosome 7 Gain Compensates for Chromosome 10 Loss in Glioma

7号染色体获得补偿了胶质瘤中10号染色体的缺失

Nair, Nishanth Ulhas; Schäffer, Alejandro A; Gertz, E Michael; Cheng, Kuoyuan; Zerbib, Johanna; Sahu, Avinash Das; Leor, Gil; Shulman, Eldad D; Aldape, Kenneth D; Ben-David, Uri; Ruppin, Eytan

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues

绘制原发性和转移性癌症的转录组图谱,并分析其与起源和靶向正常组织的关系

Sanghvi, Neel; Calvo-Alcañiz, Camilo; Rajagopal, Padma S; Scalera, Stefano; Canu, Valeria; Sinha, Sanju; Schischlik, Fiorella; Wang, Kun; Madan, Sanna; Shulman, Eldad; Papanicolau-Sengos, Antonios; Blandino, Giovanni; Ruppin, Eytan; Nair, Nishanth Ulhas

A landscape of response to drug combinations in non-small cell lung cancer

非小细胞肺癌药物联合治疗反应概况

Nair, Nishanth Ulhas; Greninger, Patricia; Zhang, Xiaohu; Friedman, Adam A; Amzallag, Arnaud; Cortez, Eliane; Sahu, Avinash Das; Lee, Joo Sang; Dastur, Anahita; Egan, Regina K; Murchie, Ellen; Ceribelli, Michele; Crowther, Giovanna S; Beck, Erin; McClanaghan, Joseph; Klump-Thomas, Carleen; Boisvert, Jessica L; Damon, Leah J; Wilson, Kelli M; Ho, Jeffrey; Tam, Angela; McKnight, Crystal; Michael, Sam; Itkin, Zina; Garnett, Mathew J; Engelman, Jeffrey A; Haber, Daniel A; Thomas, Craig J; Ruppin, Eytan; Benes, Cyril H

Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome

基于肿瘤转录组的临床导向型患者对靶向治疗和免疫疗法反应预测

Dinstag, Gal; Shulman, Eldad D; Elis, Efrat; Ben-Zvi, Doreen S; Tirosh, Omer; Maimon, Eden; Meilijson, Isaac; Elalouf, Emmanuel; Temkin, Boris; Vitkovsky, Philipp; Schiff, Eyal; Hoang, Danh-Tai; Sinha, Sanju; Nair, Nishanth Ulhas; Lee, Joo Sang; Schäffer, Alejandro A; Ronai, Ze'ev; Juric, Dejan; Apolo, Andrea B; Dahut, William L; Lipkowitz, Stanley; Berger, Raanan; Kurzrock, Razelle; Papanicolau-Sengos, Antonios; Karzai, Fatima; Gilbert, Mark R; Aldape, Kenneth; Rajagopal, Padma S; Beker, Tuvik; Ruppin, Eytan; Aharonov, Ranit

Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma

基因组和转录组分析可识别预后基因特征并预测胸膜和腹膜间皮瘤的治疗反应。

Nair, Nishanth Ulhas; Jiang, Qun; Wei, Jun Stephen; Misra, Vikram Alexander; Morrow, Betsy; Kesserwan, Chimene; Hermida, Leandro C; Lee, Joo Sang; Mian, Idrees; Zhang, Jingli; Lebensohn, Alexandra; Miettinen, Markku; Sengupta, Manjistha; Khan, Javed; Ruppin, Eytan; Hassan, Raffit