日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic modifiers of APOE-ε4-associated cognitive decline

APOE-ε4相关认知衰退的遗传修饰因子

Contreras, Alex G; Walters, Skylar; Eissman, Jaclyn M; Archer, Derek B; Regelson, Alexandra N; Durant, Alaina; Clifton, Michelle; Mukherjee, Subhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Trittschuh, Emily H; Mez, Jesse; Bush, William S; Kunkle, Brian W; Cruchaga, Carlos; Naj, Adam C; Gifford, Katherine A; Bilgel, Murat; Kuzma, Amanda B; Cuccaro, Michael L; Pericak-Vance, Margaret A; Farrer, Lindsay A; Wang, Li-San; Schellenberg, Gerard D; Haines, Jonathan L; Jefferson, Angela L; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Thompson, Paul M; Martin, Eden R; Albert, Marilyn S; Johnson, Sterling C; Engelman, Corinne D; Ferrucci, Luigi; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Sperling, Reisa A; Resnick, Susan M; Crane, Paul K; Dumitrescu, Logan; Hohman, Timothy J

Neuroimaging PheWAS and molecular phenotyping implicate PSMC3 in Alzheimer's disease

神经影像学、表型关联研究(PheWAS)和分子表型分析表明PSMC3与阿尔茨海默病有关。

Bledsoe, Xavier; Wang, Ting-Chen; Wu, Yiyang; Archer, Derek; Chen, Hung Hsin; Naj, Adam C; Bush, William S; Hohman, Timothy J; Dumitrescu, Logan; Below, Jennifer E; Gamazon, Eric R

Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers

评估载脂蛋白E基因型与超龄者认知韧性的关联

Durant, Alaina; Mukherjee, Shubhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Klinedinst, Brandon S; Trittschuh, Emily H; Mez, Jesse; Farrer, Lindsay A; Gifford, Katherine A; Cruchaga, Carlos; Hassenstab, Jason; Naj, Adam C; Wang, Li-San; Johnson, Sterling C; Engelman, Corinne D; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Cuccaro, Michael L; Kunkle, Brian W; Pericak-Vance, Margaret A; Martin, Eden R; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Bush, William S; Haines, Jonathan L; Mayeux, Richard; Vardarajan, Badri N; Albert, Marilyn S; Thompson, Paul M; Jefferson, Angela L; Crane, Paul K; Dumitrescu, Logan; Archer, Derek B; Hohman, Timothy J; Gaynor, Leslie S

Leveraging genetic propensity to identify modifiable factors for the age at onset of Alzheimer's disease

利用遗传倾向来识别阿尔茨海默病发病年龄的可改变因素

Li, Yi-Ju; La, Jong Ok; Naj, Adam; Martin, Eden R

Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities

不同种族和民族中APOE4介导的晚发性阿尔茨海默病风险与加性关系的偏差

Durodoye, Razaq O; Ciesielski, Timothy H; Benchek, Penelope; Bartlett, Jacquelaine; Zhu, Xiaofeng; Liu, Shiying; Naj, Adam; Kunkle, Brian; Schellenberg, Gerard D; Mayeux, Richard; Farrer, Lindsay; Wang, Li-San; Pericak-Vance, Margaret A; Rajabli, Farid; Tosto, Giuseppe; Haines, Jonathan L; Bush, William S; Williams, Scott M

GrafAnc: Reliable and reproducible inference of continental and regional population structure

GrafAnc:可靠且可重复地推断大陆和区域人口结构

Jin, Yumi; Wang, Hui; Naj, Adam C; Wang, Li-San; Lee, Wan-Ping

Application of the STAAR framework in detecting rare variant associations with Alzheimer disease and related dementias: Insights and implications

应用STAAR框架检测罕见变异与阿尔茨海默病及相关痴呆症的关联:见解与启示

Wang, Dongyu; Abbruzzese, Sabrina; Heard-Costa, Nancy; Rampersaud, Andy; Martin, Eden; Naj, Adam; Akgun, Bilcag; Kunkle, Brian; Seshadri, Sudha; Peloso, Gina; DeStefano, Anita L; Li, Zilin; Li, Xihao; Choi, Seung Hoan

Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort

一项多中心尸检队列研究中阿尔茨海默病及相关痴呆症神经病理学病变的全基因组关联研究荟萃分析

Cholerton, Brenna; Godrich, Dana; Pasteris, Jeremy; Rivero, Joe; Martin, Eden R; Kunkle, Brian W; Naj, Adam C; Hamilton-Nelson, Kara L; Wang, Hui; Lee, Wan-Ping; Dumitrescu, Logan; Hohman, Timothy J; Mayeux, Richard; Larson, Eric B; Crane, Paul K; Keene, C Dirk; Latimer, Caitlin S; Mukherjee, Shubhabrata; Kofler, Julia K; Kamboh, M Ilyas; Bennett, David A; Molina-Porcel, Laura; Cuccaro, Michael; Pericak-Vance, Margaret A; Rundek, Tatjana; Scott, William K; Kukull, Walter; Schellenberg, Gerard; Beecham, Gary W; Montine, Thomas J

Rare coding variants from ADSP R5 whole-genome sequencing implicate novel genes in Alzheimer's disease

来自 ADSP R5 全基因组测序的罕见编码变异揭示了与阿尔茨海默病相关的新基因

Lee, Wan-Ping; Wang, Hui; Leung, Yuk Yee; Cheng, Po-Liang; Zheng, Wendi; Valladares, Otto; Chung, Wei-Hsuan; Kuzma, Amanda; Naj, Adam; Vardarajan, Badri; Grsiwold, Anthony; Haines, Jonathan; Wang, Li-San; Schellenberg, Gerard

Association of neurodevelopmental conditions with Alzheimer's disease and related dementias and Parkinson's disease

神经发育障碍与阿尔茨海默病及相关痴呆症和帕金森病之间的关联

Rast, Jessica E; Rosso, Andrea L; James, Bryan D; Underwood, Jack F G; Bergstedt, Jacob; Ahlqvist, Viktor H; Grove, Jakob; Fang, Fang; Goldstein, Neal D; Vivanti, Giacomo; Levine, Stephen Z; Nordström, Anna; Schendel, Diana; Lyall, Kristen; Nordström, Peter; Ballin, Marcel; Stafford, Jean; Naj, Adam C; Lee, Brian K