日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The next-generation polyene EL219 is efficacious in an experimental model of central nervous system coccidioidomycosis caused by Coccidioides immitis

新一代聚烯EL219在由粗球孢子菌引起的中枢神经系统球孢子菌病实验模型中显示出疗效。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01469-25
Wiederhold, Nathan P; Najvar, Laura K; Jaramillo, Rosie; Olivo, Marcos; Patterson, Thomas F
神经科学
发表日期：2026
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The novel second-generation triterpenoid SCY-247 maintains in vitro and in vivo activity against resistant Candida glabrata

新型第二代三萜类化合物SCY-247对耐药性光滑念珠菌具有体外和体内活性。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01625-25
Wiederhold, Nathan P; Najvar, Laura K; Jaramillo, Rosie; Olivo, Marcos; Patterson, Hoja P; Patterson, Thomas F
发表日期：2026
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Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B

在嗜中性粒细胞减少的小鼠肺毛霉菌病模型中，伊布沙芬普作为单药治疗以及与脂质体两性霉素B联合治疗均有效。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01545-23
Gebremariam, Teclegiorgis; Alkhazraji, Sondus; Gu, Yiyou; Najvar, Laura K; Borroto-Esoda, Katyna; Patterson, Thomas F; Filler, Scott G; Wiederhold, Nathan P; Ibrahim, Ashraf S
细胞生物学
中性粒细胞
粒细胞
发表日期：2024
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Evaluation of nikkomycin Z with frequent oral administration in an experimental model of central nervous system coccidioidomycosis

在实验性中枢神经系统球孢子菌病模型中评估频繁口服尼克霉素Z的疗效

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.01356-24
Wiederhold, Nathan P; Najvar, Laura K; Jaramillo, Rosie; Olivo, Marcos; Larwood, David J; Patterson, Thomas F
神经科学
发表日期：2024
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High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms

利用高通量筛选药物再利用中心库，鉴定对白色念珠菌和耳念珠菌生物膜具有新型抑制活性的药物

期刊:Journal of Fungi
影响因子:4
doi:10.3390/jof9090879
Ajetunmobi, Olabayo H; Wall, Gina; Vidal Bonifacio, Bruna; Martinez Delgado, Lucero A; Chaturvedi, Ashok K; Najvar, Laura K; Wormley, Floyd L Jr; Patterson, Hoja P; Wiederhold, Nathan P; Patterson, Thomas F; Lopez-Ribot, Jose L
微生物学
发表日期：2023
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Ibrexafungerp Demonstrates In Vitro Activity against Fluconazole-Resistant Candida auris and In Vivo Efficacy with Delayed Initiation of Therapy in an Experimental Model of Invasive Candidiasis

Ibrexafungerp 在体外对耐氟康唑的耳念珠菌表现出活性，并在侵袭性念珠菌病实验模型中显示出延迟治疗的体内疗效。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02694-20
Wiederhold, Nathan P; Najvar, Laura K; Olivo, Marcos; Morris, Kelsey N; Patterson, Hoja P; Catano, Gabriel; Patterson, Thomas F
发表日期：2021
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Evaluation of Sex Differences in Murine Diabetic Ketoacidosis and Neutropenic Models of Invasive Mucormycosis

小鼠糖尿病酮症酸中毒和侵袭性毛霉菌病中性粒细胞减少模型的性别差异评估

期刊:Journal of Fungi
影响因子:
doi:10.3390/jof7040313
Teclegiorgis Gebremariam, Sondus Alkhazraji, Abdullah Alqarihi, Nathan P Wiederhold, Laura K Najvar, Thomas F Patterson, Scott G Filler, Ashraf S Ibrahim
代谢
糖尿病
粒细胞
发表日期：2021
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The Novel Arylamidine T-2307 Demonstrates In Vitro and In Vivo Activity against Candida auris

新型芳基脒类化合物T-2307在体外和体内均表现出对耳念珠菌的活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02198-19
Wiederhold, Nathan P; Najvar, Laura K; Jaramillo, Rosie; Olivo, Marcos; Patterson, Hoja; Connell, April; Fukuda, Yoshiko; Mitsuyama, Junichi; Catano, Gabriel; Patterson, Thomas F
发表日期：2020
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Extended-Interval Dosing of Rezafungin against Azole-Resistant Aspergillus fumigatus

延长瑞扎芬净给药间隔治疗唑类耐药烟曲霉

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01165-19
Wiederhold, Nathan P; Najvar, Laura K; Jaramillo, Rosie; Olivo, Marcos; Wickes, Brian L; Catano, Gabriel; Patterson, Thomas F
发表日期：2019
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Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis

在小鼠耳念珠菌侵袭性念珠菌病模型中，延迟使用福斯马诺吉匹（APX001）治疗的疗效

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01120-19
Wiederhold, Nathan P; Najvar, Laura K; Shaw, Karen J; Jaramillo, Rosie; Patterson, Hoja; Olivo, Marcos; Catano, Gabriel; Patterson, Thomas F
发表日期：2019
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