日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Designing 5' UTR sequences improves the capacity of mRNA therapeutics in preclinical models of aging and obesity.

设计 5' UTR 序列可以提高 mRNA 疗法在衰老和肥胖的临床前模型中的疗效。

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.12.060
Yoon Subin, Cho Hyeonggon, Lee Jisun, Ha Sunghyun, Lee Suyeon, Lee Yu-Sun, Cho Youngran, Ha Dahyeon, Oh Ayoung, Lee Seonghyun, Jeong Dahee, Cho Jun, Park Sang-In, Nam Jae-Hwan, Lee Young-Suk
衰老
肥胖
发育与干细胞
发表日期：2026
文献求助 收藏

Development and Validation of an Enzyme-Linked Immunosorbent Assay for Measuring Factor XI in Intravenous Immunoglobulin Products by Mitigating Heterophilic Antibody Interference

通过减少异嗜性抗体干扰，开发和验证用于测量静脉注射免疫球蛋白产品中因子XI的酶联免疫吸附试验

期刊:Journal of Microbiology and Biotechnology
影响因子:3.1
doi:10.4014/jmb.2601.01027
Kim, Yeon-Jung; Lee, Hyewon; Hong, Jeungwoon; Lee, Yeeun; Nam, Jae-Hwan
ELISA
免疫/内分泌
发表日期：2026
文献求助 收藏

Rapid-Turnaround Co-Administration of mRNA-Based MHC-I and MHC-II-Restricted Neoantigens Enhances Immune Responses of Antigen-Specific CD8(+) T Cells and Anti-Cancer Efficacy in Colorectal Cancer.

快速联合应用基于 mRNA 的 MHC-I 和 MHC-II 限制性新抗原可增强抗原特异性 CD8(+) T 细胞的免疫反应和结直肠癌的抗癌疗效。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202506426
Cho Seongje, Kwak Woori, Yoon Hyunho, Lee Jisun, Lee Seonghyun, Park Hyo-Jung, Jo Sohee, Lee Yu-Sun, Seo Yu-Jeong, Cho Youngran, Bae Seo-Hyeon, Yoon Subin, Roh Gahyun, Ha Dahyeon, Oh Ayoung, Choi Eun-Jin, Lee Soo-Yeon, Choi Huijeong, Kim Jungmin, Lee Yeeun, Lee Sowon, Park Sang-In, Kim Dae-Keun, Chang Jun, Kim Ki Tae, Kim Kwoneel, Nam Jae-Hwan
肿瘤
肠癌
T细胞
肿瘤免疫
CD8
细胞生物学
免疫/内分泌
发表日期：2025
文献求助 收藏

ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.

ApoE 缺乏可防止在代谢压力下注射部位发生 mRNA 疫苗引起的线粒体功能障碍。

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.119545
Cho Sun-Hee, Choi Byeongkwon, Lee Jisun, Lee Yu-Sun, Baek Mi-Ock, Lee You-Jeung, Gil Chae-Ok, Choi Min-Kyung, Khaliq Sana Abdul, Maham Syeda, Hyun Jae-Kyung, Roh Gahyun, Choi Huijeong, Lee Sowon, Bae Seo-Hyeon, Lee Seonghyun, Park Hyo-Jung, Ahn Jae-Hun, Lee Na-Young, Kang Byeong-Cheol, Seo Young Kyo, Lim Byung-Kwan, Nam Jae-Hwan, Rho Mina, Yoon Mee-Sup
代谢
APOE
线粒体
发表日期：2025
文献求助 收藏

3AIM-seq: Quality assessment of mRNA therapeutics using sequencing for 3' poly(A) tails of in vitro-transcribed mRNA

3AIM-seq：利用体外转录mRNA的3' poly(A)尾测序进行mRNA疗法的质量评估

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.06.033
Seo, Jina; Park, Hyo-Jung; Oh, Ayoung; Jeong, Chang Beom; Kim, Sohee; Lee, Sojeong; Kim, Chuna; Chang, Hyeshik; Nam, Jae-Hwan; Park, Daechan
发表日期：2025
文献求助 收藏

Novel Less Toxic, Lymphoid Tissue-Targeted Lipid Nanoparticles Containing a Vitamin B5-Derived Ionizable Lipid for mRNA Vaccine Delivery.

新型低毒、靶向淋巴组织的脂质纳米颗粒，含有维生素 B5 衍生的可电离脂质，用于 mRNA 疫苗递送

期刊:Advanced Healthcare Materials
影响因子:9.6
doi:10.1002/adhm.202403366
Yoo Soyeon, Faisal Muhammad, Bae Seo-Hyeon, Youn Kounghwa, Park Hyo-Jung, Kwon Sung Pil, Hwang Il Kwon, Lee Jisun, Kim Hyeong Jun, Nam Jae-Hwan, Keum Gyochang, Bang Eun-Kyoung
其它
发表日期：2025
文献求助 收藏

Impact of administration routes and dose frequency on the toxicology of SARS-CoV-2 mRNA vaccines in mice model.

给药途径和剂量频率对SARS-CoV-2 mRNA疫苗在小鼠模型中的毒理学影响

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-024-03912-1
Ahn Jae-Hun, Lee Jisun, Roh Gahyun, Lee Na-Young, Bae Hee-Jin, Kwon Euna, Han Kang-Min, Kim Ji-Eun, Park Hyo-Jung, Yoo Soyeon, Kwon Sung Pil, Bang Eun-Kyoung, Keum Gyochang, Nam Jae-Hwan, Kang Byeong-Cheol
新冠
发表日期：2025
文献求助 收藏

Integration of TLR7/8 agonists into lipid nanoparticles enhances antigen-specific immune responses to N1-methyl-Ψ-modified mRNA-LNP vaccines

将TLR7/8激动剂整合到脂质纳米颗粒中可增强针对N1-甲基-Ψ修饰的mRNA-LNP疫苗的抗原特异性免疫反应

期刊:Journal of Biological Engineering
影响因子:6.5
doi:10.1186/s13036-025-00573-1
Choi, Huijeong; Lee, Seonghyun; Kim, Hyejin; Bae, Seo-Hyeon; Jo, Sohee; Kim, Jungmin; Lee, Yeeun; Ha, Dahyeon; Oh, Ayoung; Yoon, Subin; Jeon, Sanghyuk; Lee, Yu-Sun; Cho, Youngran; Cho, Seongje; Roh, Gahyun; Lee, Sowon; Gowda, Jayaraj; Park, Hyo-Jung; Lee, Jisun; Song, Daesub; Hong, So-Hee; Han, Soo Bong; Nam, Jae-Hwan
TLR7
免疫/内分泌
发表日期：2025
文献求助 收藏

A20 mRNA therapeutics ameliorate systemic sclerosis by suppressing TRAF-6/NF-KB signaling and DREAM expression and exerting antifibrotic effects.

A20 mRNA 疗法通过抑制 TRAF-6/NF-KB 信号传导和 DREAM 表达并发挥抗纤维化作用来改善系统性硬化症。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1665998
Lee A Ram, Jeon Su Been, Kwak Hye Won, Yang Suh Won, Bang Yoo Jin, Lee Seon-Yeong, Lee So Won, Park Jin Hyung, Han Se Gyeong, Choi Jeong Won, Park Hyo-Jung, Cho Mi-La, Nam Jae-Hwan
系统性硬化症
信号转导
发表日期：2025
文献求助 收藏

Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method.

利用新型加帽文库筛选方法，发现并开发出安全有效的 COVID-19 mRNA 疫苗 STP2104

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1571713
Choi Kanghyun, Lee Joo-Young, Kim Uk-Il, Park So-Hyun, Hong So-Hee, Bang Yoo-Jin, Hwang Yun-Ho, Lee Jong-Eun, Park Suhyun, Kim Soochong, Lee Sunhee, Yun Ye-Jin, Uhm Tae-Gi, Lee Inyoung, Kwon Minju, Kwon EunJi, Song Suyeon, Kweon Yongkyoung, Kim Heejene, Oh Eun-Young, Kim Jae-Yong, Lee Tae-Young, Kim Seo-Yeon, Kim Se-Eun, Kim You-Jin, Lee Seonock, Sun Ruijing, Lee Eun-Joo, Kim Gamin, Lim Hanah, Kim Byungkyun, Kim Jungho, Kim Dokeun, Nam Jae-Hwan, Lee Sang-Myeong, Kim Kyungjin, Yang Joo-Sung
其它
发表日期：2025
文献求助 收藏