Nandadasa Sumeda相关文献与解析，生知库 | 链接生命科学的每一步

Stuck, Michael W; Gupta, Mohona; Knutson, Luke N; Desai, Paurav B; Robert, Karyn L; Anuszczyk, Jeffrey J; Smith, Abigail O; Paulson, Delayna; Nandadasa, Sumeda; Devine, William; Lo, Cecilia W; Cox, Timothy C; Fink, Darci M; Pazour, Gregory J

发表日期：2026

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Loss of ADAMTS9 disrupts ciliogenesis and collagen homeostasis resulting in Nephronophthisis-like polycystic kidneys

ADAMTS9 的缺失会破坏纤毛发生和胶原蛋白稳态，导致类似肾痨的多囊肾。

期刊:

影响因子:

doi:10.64898/2025.12.02.691883

Fischer, Sydney; Robert, Karyn L; Ahmed, Manu; Kane, Griffin I; Kavanaugh, Matthew A; Wang, Wei; Tran, Pamela V; Atukorale, Prabhani U; Nandadasa, Sumeda

ADA

发表日期：2026

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Cleavage of the Meckel-Gruber syndrome protein TMEM67 by ADAMTS9 uncouples Wnt signaling and ciliogenesis.

ADAMTS9 对 Meckel-Gruber 综合征蛋白 TMEM67 的切割可使 Wnt 信号传导与纤毛发生解耦联

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-60294-3

Ahmed Manu, Fischer Sydney, Robert Karyn L, Lange Karen I, Stuck Michael W, Best Sunayna, Johnson Colin A, Pazour Gregory J, Blacque Oliver E, Nandadasa Sumeda

信号转导

发表日期：2025

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Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis.

由 ADAMTS9 蛋白水解切割产生的 Meckel-Gruber 综合征蛋白 TMEM67 的两种功能形式介导 Wnt 信号传导和纤毛发生

期刊:

影响因子:

doi:10.1101/2024.09.04.611229

Ahmed Manu, Fischer Sydney, Robert Karyn L, Lange Karen I, Stuck Michael W, Best Sunayna, Johnson Colin A, Pazour Gregory J, Blacque Oliver E, Nandadasa Sumeda

信号转导

发表日期：2024

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A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu(441)-Ala(442) peptide bond in the V1 isoform is essential for interdigital web regression

一种具有抗切割versican蛋白的新型小鼠突变体和异构体特异性versican突变体表明，V1异构体中Glu(441)-Ala(442)肽键的蛋白水解对于趾间蹼的退化至关重要。

期刊:Matrix Biology Plus

影响因子:

doi:10.1016/j.mbplus.2021.100064

Nandadasa, Sumeda; Burin des Roziers, Cyril; Koch, Christopher; Tran-Lundmark, Karin; Dours-Zimmermann, María T; Zimmermann, Dieter R; Valleix, Sophie; Apte, Suneel S

发表日期：2021

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ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation

ADAMTS9介导的细胞外基质动力学调控脐带血管平滑肌分化和旋转

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2015.05.005

Nandadasa, Sumeda; Nelson, Courtney M; Apte, Suneel S

The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis

在胚胎发生过程中，versican 及其通过 ADAMTS 蛋白酶进行的蛋白水解周转发挥着多种复杂的作用。

期刊:Matrix Biology

影响因子:4.8

doi:10.1016/j.matbio.2014.01.005

Nandadasa, Sumeda; Foulcer, Simon; Apte, Suneel S

ADA

发表日期：2014

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Ift43 Controls the Ciliary Levels of Gli2 and Gli3

Ift43 控制纤毛中 Gli2 和 Gli3 的水平

Loss of ADAMTS9 disrupts ciliogenesis and collagen homeostasis resulting in Nephronophthisis-like polycystic kidneys

ADAMTS9 的缺失会破坏纤毛发生和胶原蛋白稳态，导致类似肾痨的多囊肾。

Cleavage of the Meckel-Gruber syndrome protein TMEM67 by ADAMTS9 uncouples Wnt signaling and ciliogenesis.

ADAMTS9 对 Meckel-Gruber 综合征蛋白 TMEM67 的切割可使 Wnt 信号传导与纤毛发生解耦联

Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis.

由 ADAMTS9 蛋白水解切割产生的 Meckel-Gruber 综合征蛋白 TMEM67 的两种功能形式介导 Wnt 信号传导和纤毛发生

A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu(441)-Ala(442) peptide bond in the V1 isoform is essential for interdigital web regression

一种具有抗切割versican蛋白的新型小鼠突变体和异构体特异性versican突变体表明，V1异构体中Glu(441)-Ala(442)肽键的蛋白水解对于趾间蹼的退化至关重要。

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation

ADAMTS9介导的细胞外基质动力学调控脐带血管平滑肌分化和旋转

The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis

在胚胎发生过程中，versican 及其通过 ADAMTS 蛋白酶进行的蛋白水解周转发挥着多种复杂的作用。