Ethanol induction of FGF21 in the liver is dependent on histone acetylation and ligand activation of ChREBP by glycerol-3-phosphate.
乙醇诱导肝脏中 FGF21 的产生依赖于组蛋白乙酰化和甘油-3-磷酸对 ChREBP 的配体激活
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2505263122
Cheong Mi Cheong, Mackowiak Bryan, Kim Hyung Bum, Hernandez Genaro, Nandu Tulip, Vale Kevin, Zhang Yuan, Zacharias Lauren G, Mathews Thomas P, Gao Bin, Kraus W Lee, Kliewer Steven A, Mangelsdorf David J