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日期影响因子

Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically

肥厚型心肌病突变Y115H和E497D通过变构作用破坏人β-心肌肌球蛋白的折叠状态。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-63816-1

Nandwani, Neha; Bhowmik, Debanjan; Glaser, Camille; Childers, Matthew Carter; Goluguri, Rama Reddy; Dawood, Aminah; Regnier, Michael; Houdusse, Anne; Spudich, James A; Ruppel, Kathleen M

发表日期：2025

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A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motif

利用FRET检测法监测人β-心肌肌球蛋白的不同结构状态，包括相互作用头部基序。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2504562122

Goluguri, Rama Reddy; Guhathakurta, Piyali; Nandwani, Neha; Dawood, Aminah; Yokota, Seiji; Roopnarine, Osha; Thomas, David D; Ruppel, Kathleen M; Spudich, James A

发表日期：2025

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Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy

重新评估肥厚型心肌病中肌球蛋白突变引起的过度收缩的统一假说

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/s44318-024-00199-x

Spudich, James A; Nandwani, Neha; Robert-Paganin, Julien; Houdusse, Anne; Ruppel, Kathleen M

发表日期：2024

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Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically

肥厚型心肌病突变Y115H和E497D通过变构作用破坏人β-心肌肌球蛋白的折叠状态。

doi:10.1101/2024.02.29.582851

Nandwani, Neha; Bhowmik, Debanjan; Childers, Matthew C; Goluguri, Rama Reddy; Dawood, Aminah; Regnier, Michael; Spudich, James A; Ruppel, Kathleen M

发表日期：2024

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A FRET assay to quantitate levels of the human Î²-cardiac myosin interacting heads motif based on its near-atomic resolution structure.

基于接近原子分辨率结构的FRET检测方法，可定量分析人类β-心肌肌球蛋白相互作用头部基序的水平

doi:10.1101/2024.12.05.626936

Goluguri Rama Reddy, Guhathakurta Piyali, Nandwani Neha, Dawood Aminah, Yakota Seiji, Roopnarine Osha, Thomas David D, Spudich James A, Ruppel Kathleen M

发表日期：2024

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Nanomechanical Phenotypes in Cardiac Myosin-Binding Protein C Mutants That Cause Hypertrophic Cardiomyopathy

导致肥厚型心肌病的心肌肌球蛋白结合蛋白C突变体的纳米力学表型

期刊:ACS Nano

影响因子:16

doi:10.1021/acsnano.1c02242

Suay-Corredera, Carmen; Pricolo, Maria Rosaria; Velázquez-Carreras, Diana; Pathak, Divya; Nandwani, Neha; Pimenta-Lopes, Carolina; Sánchez-Ortiz, David; Urrutia-Irazabal, Iñigo; Vilches, Silvia; Dominguez, Fernando; Frisso, Giulia; Monserrat, Lorenzo; García-Pavía, Pablo; de Sancho, David; Spudich, James A; Ruppel, Kathleen M; Herrero-Galán, Elías; Alegre-Cebollada, Jorge

发表日期：2021

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A five-residue motif for the design of domain swapping in proteins

用于蛋白质结构域交换设计的五氨基酸残基基序

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-019-08295-x

Nandwani, Neha; Surana, Parag; Negi, Hitendra; Mascarenhas, Nahren M; Udgaonkar, Jayant B; Das, Ranabir; Gosavi, Shachi

发表日期：2019

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Amino-acid composition after loop deletion drives domain swapping

环状结构缺失后的氨基酸组成驱动结构域交换

期刊:Protein Science

影响因子:5.2

doi:10.1002/pro.3237

Nandwani, Neha; Surana, Parag; Udgaonkar, Jayant B; Das, Ranabir; Gosavi, Shachi

发表日期：2017

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