日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii

利用非糖基化单克隆抗体提高柯马加塔氏菌(Komagataella phaffii)的产量

Yang, Yuchen; Dalvie, Neil C; Brady, Joseph R; Naranjo, Christopher A; Lorgeree, Timothy; Rodriguez-Aponte, Sergio A; Johnston, Ryan S; Tracey, Mary K; Elenberger, Carmen M; Lee, Eric; Tié, Mark; Love, Kerry R; Love, J Christopher

Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants.

对刺突蛋白 RBD 中隐蔽表位进行分子工程改造,可提高其生产性能和对 SARS-CoV-2 变种的中和广度

Rodriguez-Aponte Sergio A, Dalvie Neil C, Wong Ting Y, Johnston Ryan S, Naranjo Christopher A, Bajoria Sakshi, Kumru Ozan S, Kaur Kawaljit, Russ Brynnan P, Lee Katherine S, Cyphert Holly A, Barbier Mariette, Rao Harish D, Rajurkar Meghraj P, Lothe Rakesh R, Shaligram Umesh S, Batwal Saurabh, Chandrasekaran Rahul, Nagar Gaurav, Kleanthous Harry, Biswas Sumi, Bevere Justin R, Joshi Sangeeta B, Volkin David B, Damron F Heath, Love J Christopher