日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transglutaminase 2 knockout mice are protected from bleomycin-induced lung fibrosis with preserved lung function and reduced metabolic derangements

转谷氨酰胺酶 2 基因敲除小鼠可免受博来霉素诱发的肺纤维化的影响,保持肺功能,减少代谢紊乱

Margaret A T Freeberg, Thomas H Thatcher, Sarah V Camus, Linghong Huang, John Atkinson, Wade Narrow, Jeannie Haak, Andrew M Dylag, L Ashley Cowart, Timothy S Johnson, Patricia J Sime

Protocol for isolating extracellular vesicles from pancreatic cancer cells for liver metastatic niche research

从胰腺癌细胞中分离细胞外囊泡以用于肝转移性微环境研究的方案

Anthony Casabianca, Mélanie Bellina, Crissy Dudgeon, Muhammad Sadeqi Nezhad, Chris Harris, Stephany Fiore, Agnes Bernet, Wade Narrow, Orjola Prela, Lan Wang, Igor Astsaturov, Patrick Mehlen, Darren R Carpizo

Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling

Netrin-1前馈机制通过肝星状细胞活化、类视黄酸和ELF3信号通路促进胰腺癌肝转移

Crissy Dudgeon ,Anthony Casabianca ,Chris Harris ,Charline Ogier ,Mélanie Bellina ,Stephany Fiore ,Agnes Bernet ,Benjamin Ducarouge ,David Goldschneider ,Xiaoyang Su ,Jason Pitarresi ,Aram Hezel ,Subhajyoti De ,Wade Narrow ,Fady Soliman ,Cory Shields ,Debora Barbosa Vendramini-Costa ,Orjola Prela ,Lan Wang ,Igor Astsaturov ,Patrick Mehlen ,Darren R Carpizo

Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies

在三转基因阿尔茨海默病小鼠中,慢性神经元和年龄选择性下调TNF受体表达可显著调节淀粉样蛋白和Tau蛋白相关的病理。

Montgomery, Sara L; Narrow, Wade C; Mastrangelo, Michael A; Olschowka, John A; O'Banion, M Kerry; Bowers, William J

An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction

阿尔茨海默病相关的早老素-1突变会增强淀粉样β蛋白诱导的少突胶质细胞功能障碍

Maya K Desai, Brendan J Guercio, Wade C Narrow, William J Bowers

Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain

消除阿尔茨海默病小鼠的 TNF-RI/RII 表达会导致病理学意外增强:对大脑中慢性泛 TNF-α 抑制治疗策略的影响

Sara L Montgomery, Michael A Mastrangelo, Diala Habib, Wade C Narrow, Sara A Knowlden, Terry W Wright, William J Bowers

Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

通过对流增强递送 AAV2-GDNF 可促进 MPTP 损伤的多巴胺能系统的再生

Kells Adrian P, Eberling Jamie, Su Xiaomin, Pivirotto Philip, Bringas John, Hadaczek Piotr, Narrow Wade C, Bowers William J, Federoff Howard J, Forsayeth John, Bankiewicz Krystof S

Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target

阿尔茨海默病小鼠早期少突胶质细胞/髓鞘病变构成了一种新的治疗靶点

Desai, Maya K; Mastrangelo, Michael A; Ryan, Deborah A; Sudol, Kelly L; Narrow, Wade C; Bowers, William J

Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease

生成差异化靶向淀粉样β蛋白特异性胞内抗体作为阿尔茨海默病的被动疫苗接种策略

Kelly L Sudol, Michael A Mastrangelo, Wade C Narrow, Maria E Frazer, Yona R Levites, Todd E Golde, Howard J Federoff, William J Bowers

Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice

干扰素-γ对阿尔茨海默病病理有不同影响,并在三重转基因阿尔茨海默病小鼠中诱导神经发生

Michael A Mastrangelo, Kelly L Sudol, Wade C Narrow, William J Bowers